This article will focus on benzene sulfonyl chloride and its effects on worker health. Benzene sulfonyl chloride is a chemical compound widely used in many industries, but it also carries significant risks for those in direct contact. We will go into detail to understand the impact of this compound on health and propose necessary safety measures to protect workers during their work with benzene sulfonyl chloride.
1. What is Benzene sulfonyl chloride?
Benzene sulfonyl chloride, also known as benzenesulfonyl chloride or benzene sulfonic chloride, is a chemical compound with the chemical formula C6H5O2ClS. It is a form of sulfonyl chloride, in which the sulfonyl group (SO2) is combined with a benzene ring (C6H5). The chemical structure of benzene sulfonyl chloride is:
Benzene sulfonyl chloride is often used in many industrial applications, including as a raw material for the synthesis of other chemicals, in organic chemical reactions, and can be used in the production of pharmaceuticals and cosmetics. However, for workers in direct contact with this substance, safety measures must be implemented as benzene sulfonyl chloride can be harmful to health.
| No. | Chemical Name in Vietnamese | Chemical Name in English | HS Code | CAS Number | Chemical Formula |
| 1. | Benzen sunphonyl clorua | Benzene sulfonyl chloride | 29049000 | 98-09-9 | C6H5O2ClS |
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2. Where does Benzene sulfonyl chloride originate from in the production process?
Benzene sulfonyl chloride (C6H5SO2Cl) is typically produced through chemical methods. This production process usually starts with benzenesulfonic acid (C6H5SO3H), a compound that can be made from benzene (C6H6) and sulfur trioxide (SO3) gas in an acidic environment. Below is a detailed description of the production process for benzene sulfonyl chloride:
- Creating Benzenesulfonic Acid (C6H5SO3H):
- Benzene (C6H6) reacts with sulfur trioxide (SO3) gas in a sulfonic acid (H2SO4) environment. This reaction creates benzenesulfonic acid (C6H5SO3H).
C6H6 + SO3 → C6H5SO3H (H2SO4 catalyst)
- Conversion to Benzene Sulfonyl Chloride (C6H5SO2Cl):
- Benzenesulfonic acid then reacts with thionyl chloride (SOCl2), producing benzene sulfonyl chloride (C6H5SO2Cl) and hydrochloric acid (HCl).
C6H5SO3H + SOCl2 → C6H5SO2Cl + HCl
This process creates benzene sulfonyl chloride, a compound primarily used in chemical synthesis processes and pharmaceutical production. However, attention must be paid to safety management during the production and use of this substance due to its health-affecting properties.

3. Industries that use Benzene sulfonyl chloride in production
Benzene sulfonyl chloride (C6H5SO2Cl) is used in several different industries due to its chemical properties. Here are some industries that may use benzene sulfonyl chloride in their production processes:
- Chemical Industry:
- Benzene sulfonyl chloride is often used as an intermediate in the synthesis of other chemical compounds, especially sulfonyl chloride derivatives.
- Pharmaceutical Industry:
- Benzene sulfonyl chloride may be used in the production process of pharmaceuticals and biomedical chemicals.
- Cosmetics Manufacturing Industry:
- Benzene sulfonyl chloride may be used to produce ingredients in cosmetic and personal care products.
- Colorant and Dye Manufacturing Industry:
- Benzene sulfonyl chloride can be applied in the colorant and dye manufacturing industry.
- Pharmaceutical Materials Industry:
- In the pharmaceutical field, benzene sulfonyl chloride can be used to create important compounds for drug production.
- Rubber and Plastic Additives Manufacturing Industry:
- Benzene sulfonyl chloride may be used in the process of manufacturing additives for rubber and plastics.
- Essential Oils and Fragrances Industry:
- Benzene sulfonyl chloride may be used to create aromatic compounds in the essential oil and fragrance industry.
4. How does Benzene sulfonyl chloride affect workers?
Benzene sulfonyl chloride can affect the health of workers when they have direct or unsafe contact with this substance during production and use. Here are some typical effects:
- Skin and Eye Irritation:
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- Benzene sulfonyl chloride can cause skin irritation and burns upon direct contact. If this substance contacts the eyes, it can cause pain, redness, and severe damage.
- Impact on the Respiratory System:
- Vapors or dust of benzene sulfonyl chloride, if inhaled, can irritate the respiratory tract and may cause difficulty breathing, chest pain, and other respiratory-related problems.
- Risk of Impact on the Nervous System:
- Some chemical compounds can pose a risk of impacting the nervous system. Although not always the case, long-term or high-level exposure can affect the nervous system.
- Risk of Impact on the Digestive System:
- Contact with benzene sulfonyl chloride can cause problems in the digestive system, especially if the substance is swallowed.
- Risk of Causing Liver and Kidney Damage:
- Some chemicals can affect the liver and kidneys when workers are exposed to them, especially through inhalation or skin contact.
- Risk of Impact on the Blood System:
- Some chemicals can affect the blood system, and benzene sulfonyl chloride may pose a similar risk if workers are exposed to it unsafely.
5. Permissible safe concentration of Benzene sulfonyl chloride for human exposure
The permissible safe concentration of benzene sulfonyl chloride (C6H5SO2Cl) for human exposure can depend on many factors such as the type of contact (inhalation, skin contact, ingestion), duration of exposure, and working conditions. Regulatory agencies and health organizations regularly establish safety standards for chemical substances to protect worker health.
At high levels, benzene sulfonyl chloride can be harmful to health, and therefore, safe concentration limits are usually set to reduce risk. Specifically, safe concentration limits may be determined through safety management systems such as TLV (Threshold Limit Value) or Occupational Safety and Health Administration (OSHA). These values may vary depending on the regulations of each country.

6. Measures to minimize the effects of Benzene sulfonyl chloride on worker health
To minimize the effects of Benzene sulfonyl chloride on worker health, safety measures and risk management must be implemented. Here are some important measures:
- Use Personal Protective Equipment (PPE):
- Ensure that workers in direct contact with Benzene sulfonyl chloride are equipped with full PPE, including safety goggles, respirators, gloves, chemical-resistant clothing, and safety footwear.
- Implement Safe Work Procedures:
- Develop and implement safe work procedures to reduce the risk of unsafe exposure to Benzene sulfonyl chloride. This includes identifying and enforcing risk control measures.
- Use Ventilation and Local Exhaust Systems:
- Use ventilation and local exhaust systems to reduce the nature of Benzene sulfonyl chloride vapors and dust during production and handling.
- Occupational safety training:
- Train workers on the risks and safety measures when working with Benzene sulfonyl chloride. Clearly communicate the hazards and how to implement safety measures.
- Control Exposure Time and Level:
- Limit the exposure time and level of workers to Benzene sulfonyl chloride, especially in high-concentration environments.
- Risk Management and Regular Assessment:
- Conduct regular risk assessments and maintain an effective risk management system to ensure that safety measures are working correctly.
- Use Safer Alternatives:
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- If possible, consider using safer alternative compounds to Benzene sulfonyl chloride.
- Note on Waste Disposal:
- Pay attention to the handling and disposal of waste containing Benzene sulfonyl chloride according to environmental rules and regulations.
- Periodically organize workplace environment monitoring in factories and enterprises, collect and analyze harmful factors for workers, thereby adjusting to reduce hazard levels to prevent occupational diseases for them.
7. Nationwide workplace environment monitoring center
Workplace Environment Monitoring Center of Nam Viet is a professional unit specializing in monitoring and measuring the quality of the working environment across all provinces in Vietnam. With a team of experienced monitoring specialists, the center uses modern measuring equipment, ensuring accuracy and reliability.
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8. Workplace environment monitoring quotation
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