Diazinon, an organophosphate insecticide, is widely used in agriculture and insect control. However, exposure to Diazinon can pose many serious health risks to workers, especially those working in factories producing this chemical. This article will discuss in detail the health effects of Diazinon on workers, including both acute and chronic impacts, as well as the necessary preventive measures to protect their health.
1. What is Diazinon?
Diazinon is a chemical compound with the molecular formula C12H21O3N2SP. Discovered in the 1950s, Diazinon is widely used as an organic insecticide. It is a thiophosphorate compound, which functions by stimulating the activity of the acetylcholinesterase enzyme in the nervous system of insects, leading to seizures. Diazinon is commonly used to control pests in agriculture and control insects in residential applications.
The chemical formula of Diazinon is represented by the chemical elements C (carbon), H (hydrogen), O (oxygen), N (nitrogen), S (sulfur), and P (phosphorus). This shows that Diazinon is an organic compound containing these basic elements in its molecular structure. The chemical formula C12H21O3N2SP indicates that each Diazinon molecule consists of 12 carbon atoms, 21 hydrogen atoms, 3 oxygen atoms, 2 nitrogen atoms, 1 sulfur atom, and 1 phosphorus atom.
| No. | Chemical Name in Vietnamese | Chemical Name in English | HS Code | CAS Number | Chemical Formula |
| 1. | Diazinon | Diazinon | 29335910 | 333-41-5 | C12H21O3N2SP |
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2. Where does Diazinon originate from in the production process?
Diazinon is a synthetic chemical compound produced through a complex chemical synthesis process. The main raw materials for producing Diazinon include various chemical compounds and products. One of the main components to create Diazinon is phosphorothioate, a type of ester of phosphoric acid and thioacids. Phosphorothioate is a basic raw material in the chemical synthesis process of Diazinon.
The main stages in the Diazinon production process include chemical reactions combining raw materials to create the specific chemical bonds necessary for Diazinon’s structure. These reactions often require specific temperature, pressure, and catalyst conditions to proceed successfully. Afterward, the resulting product will be purified and filtered to obtain Diazinon with the desired purity.

3. Industries that use Diazinon in production
Diazinon is a chemical compound belonging to the organophosphorothioate group, widely used in industries related to agriculture and insect control. Before being banned in many countries due to its toxic risk, Diazinon was often applied in agricultural production to eliminate pests and harmful insects. In particular, Diazinon was commonly used in the production of fruits, vegetables, and other crops to protect them from various pests, fungi, and harmful insects.
Besides agriculture, Diazinon was also applied in the livestock sector to control insects harmful to herds of cattle and poultry. The use of Diazinon in livestock production aimed to ensure the health of the animals and increase productivity in the rearing process.
Furthermore, Diazinon was also applied in some other industries such as cosmetics and pharmaceuticals. In cosmetics, it could be used as a preservative. In pharmaceuticals, Diazinon was once used in some insecticide and tick-treatment products but was later withdrawn due to concerns about its negative impacts on human health.
4. How does Diazinon affect workers
Diazinon is a chemical substance that can cause many dangers to the health of workers when in direct contact during use. Workers in the agricultural and livestock production industries are the groups at highest risk of facing the impacts of Diazinon.
Workers exposed to Diazinon through activities such as spraying pesticides or handling products containing this substance are at risk of inhalation or skin contact. Diazinon can cause toxic effects on the nervous system, especially when inhaling vapors or dust containing this substance. Symptoms of Diazinon poisoning in workers can include headache, dizziness, nausea, vomiting, and difficulty breathing.
In addition, long-term exposure to Diazinon can also cause problems with the respiratory and digestive systems. Studies have also shown that Diazinon can cause serious effects on the liver and kidneys in cases of repeated or high-volume exposure.
5. Permissible safe concentration of Diazinon for human exposure
The permissible safe concentration of Diazinon for human exposure is an important issue regulated to ensure the health of employees and the community. Typically, international organizations such as the World Health Organization (WHO) and the U.S. Food and Drug Administration (FDA) have issued guidelines on the safe concentration of Diazinon upon exposure.
According to WHO standards, the permissible safe concentration of Diazinon for short-term exposure (in one day) is about 0.03 mg/kg of a person’s body weight. For long-term exposure, WHO recommends the concentration should not exceed 0.001 mg/kg of body weight per day. These guidelines are established to minimize the toxic risk to humans from the use of Diazinon in production activities.
In the United States, the FDA has also established safe limits for Diazinon concentrations in food products. According to the FDA, the safe concentration of Diazinon in fruits and vegetables is below 0.03 ppm (parts per million). This means that the concentration of Diazinon in agricultural products must be controlled to ensure safety for consumers.

At a basic level, if working in an industrial environment, it is important to adhere to safety standards and limit exposure to Diazinon. Organizations like the Occupational Safety and Health Administration (OSHA) in the United States provide guidelines and safety principles to protect workers from the negative impacts of chemical substances.
6. Measures to minimize the effects of Diazinon on workers’ health
To minimize the effects of Diazinon on workers’ health, safety measures and procedures applied during the use of this substance in agricultural and livestock production are very important. Below are specific measures that can be implemented to protect workers’ health:
Safety training and guidance: In-depth safety training on Diazinon is necessary for workers who come into direct contact with this substance. Employees need to be trained on how to use, store, and handle Diazinon safely. They also need to be instructed on the use of personal protective equipment and preventive measures to minimize the risk of unwanted exposure.
Use of personal protective equipment: Workers need to be provided with adequate personal protective equipment such as masks, gloves, chemical-resistant coats, and goggles. The use of this protective gear will help protect them from direct contact with Diazinon and reduce the risk of inhalation or skin contact.
Periodic health checks: Employees exposed to Diazinon should undergo periodic health checks to detect early signs of abnormalities and health problems related to chemical exposure.
Use of safer alternative products: To reduce reliance on Diazinon, manufacturers should consider using pesticides and chemicals that are safer for humans and the environment.
Waste management and safe disposal: The disposal and destruction of Diazinon are also very important to avoid environmental pollution and the risk of accidental exposure. Chemical waste disposal processes must comply with environmental and occupational safety regulations.
Occupational safety training: Workers need to be trained and educated about the risks and safety measures when working with this type of chemical. This training should be provided periodically and frequently to ensure understanding and proper compliance with safety rules.
Periodically organize workplace environment monitoring in factories and enterprises, collect and analyze factors harmful to workers, and from there, adjust to reduce hazard levels to prevent occupational diseases for them.
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