Explore the effects of dibutyl ether (C8H18O) on the health of workers in manufacturing plants. The article will analyze the risks and health protection measures when exposed to this chemical. Let’s find out!
1. What is Dibutyl ether?
Dibutyl ether is a chemical compound with the molecular formula C8H18O. It is also called dibutyl ether or butyl ether, and is a type of ester formed from two molecules of butanol and one molecule of an acid or acid anhydride. Dibutyl ether is a normal ether compound in the simple ethers group. The chemical formula of dibutyl ether is C8H18O, where the carbon and oxygen atoms are arranged in a specific ratio.
The chemical formula C8H18O of dibutyl ether can be described in detail by determining its molecular structure. In dibutyl ether, there are eight carbon atoms, eighteen hydrogen atoms, and one oxygen atom. Written as a geometric molecule, dibutyl ether has an open-chain structure with two butyl groups (C4H9) bonded to the oxygen atom.
Butyl ether (dibutyl ether) is a common organic solvent in industrial and chemical applications. It has a high boiling point and is a non-polar solvent, often used to dissolve water-insoluble substances. The chemical structure of dibutyl ether allows it to act as a carrier in chemical processes and increase the compatibility of solvent mixtures.
| No. | Chemical Name (Vietnamese) | Chemical Name (English) | HS Code | CAS Number | Chemical Formula |
| 1. | Dibutyl ete | Dibutyl ether | 29091900 | 142-96-1 | C8H18O |
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2.Where does Dibutyl ether originate from in the production process?
Dibutyl ether is often produced through a chemical synthesis process from butanol. The production process mainly includes two main stages: first is the oxidation of butanol to butyric anhydride, then the trimerization of butyric anhydride to create dibutyl ether.
In the first stage, butanol (C4H9OH) is oxidized to create butyric anhydride (C4H7OOCOCH3). This process is often carried out through the oxidation of butanol with oxygen (O2) at high temperatures in a catalytic environment. Butyric anhydride is an important intermediate in the production of dibutyl ether.
After that, butyric anhydride is trimerized to form dibutyl ether (C8H18O). In this stage, two molecules of butyric anhydride react with each other in a suitable catalytic environment, producing dibutyl ether and by-products.

3. Industries that use Dibutyl ether in production
Dibutyl ether (also known as dibutyl ether) is an organic compound with applications in many different industrial fields. One of the main industries that uses Dibutyl ether is the chemical production industry. Dibutyl ether is often used as a solvent in the synthesis of other organic compounds, especially in the production of colorants, pharmaceuticals, and industrial chemicals.
Dibutyl ether is also an important component in the printing ink and paint manufacturing industry. Dibutyl ether has good solubility with many types of inks and resins, helping to increase the viscosity and uniformity of the printing ink. This characteristic helps improve the performance and quality of printing inks and paints, meeting the requirements in printing and coating production.
In addition to applications in the chemical and printing ink industries, Dibutyl ether is also used in the pharmaceutical manufacturing industry. This compound has properties as a safe, non-toxic solvent and can dissolve some types of pharmaceuticals. This is why Dibutyl ether is often used to assist in the synthesis and production of some types of drugs used in the medical field.
4. How does Dibutyl ether affect workers?
Dibutyl ether is an organic compound used in many industries, especially as a solvent and additive. However, excessive exposure to dibutyl ether can cause many negative impacts on the health of workers. It is a colorless liquid with a fragrance-like odor, but it can be dangerous when inhaled or upon long-term exposure.
One of the main problems is that dibutyl ether can cause skin and eye irritation. Direct skin contact can lead to dermatitis, rashes, and irritation. If it comes into contact with the eyes, dibutyl ether can cause pain, redness, and swelling in the eye area, causing discomfort and affecting clear vision. Therefore, workers need to comply with safety regulations, including wearing safety glasses and protective clothing to protect the skin when working with this substance.
In addition, dibutyl ether can also be dangerous when inhaled. Inhaling dibutyl ether vapor or dust can cause symptoms such as headache, dizziness, fatigue, and difficulty breathing. If exposed to high concentrations, dibutyl ether can paralyze the nervous system and affect the function of the liver and kidneys. Therefore, it is necessary to implement control measures for workers to avoid inhaling dibutyl ether, including using respiratory protection equipment and ensuring adequate ventilation when working in an environment containing vapors of this substance.
5. Permissible safe concentration of Dibutyl ether for human exposure
The permissible safe concentration of Dibutyl ether (DBE) for human exposure depends on many factors such as the type of exposure (short-term or long-term), the route of exposure (inhalation or skin contact), as well as the duration and level of exposure. DBE is a colorless, volatile liquid, often used in industrial and commercial applications.
According to the guidelines of the U.S. Occupational Safety and Health Administration (OSHA), the maximum concentration of DBE in the air that a person can be exposed to within 8 hours is 50 ppm (parts per million). This is considered a safe level for activities related to the production, processing, or use of DBE in an industrial environment. However, exposure to DBE at this level also needs to be controlled and monitored to ensure worker safety.
In cases of short-term or workplace exposure, risk assessment and limiting exposure are very important. Different safety limits may apply depending on the type of exposure. For example, to prevent the risk of inhalation, better controls such as using effective ventilation systems and wearing protective masks are necessary.
For skin contact, the use of protection such as gloves and gowns may be required to avoid direct contact with DBE. In addition, leak control measures and safe handling during the use of DBE are also important factors to ensure safety in the work environment.

At a basic level, when working in an industrial environment, it is important to comply with safety standards and limit exposure to Dibutyl ether. Organizations like the Occupational Safety and Health Administration (OSHA) in the United States provide guidelines and safety principles to protect workers from the negative impacts of chemical substances.
6. Measures to minimize the effects of Dibutyl ether on worker health
Dibutyl ether (DBE) is a toxic chemical compound that can cause many health problems for workers if exposed regularly. Fortunately, there are several effective measures that can help minimize these effects to the lowest level.
Engineering controls:
- Ventilation: Maintaining an effective ventilation system is essential to remove DBE from the work area. Local exhaust ventilation placed near the DBE emission source is necessary to prevent its spread.
- Material substitution: If possible, DBE should be replaced with less toxic solvents. This is the most effective solution to completely eliminate the risk from DBE.
- Protective equipment: Use appropriate personal protective equipment (PPE) such as gloves, protective clothing, safety glasses, and respirators. Masks must be selected appropriately for the type and concentration of DBE present in the work environment.
Safe work practices:
- Minimize exposure: Only use DBE when necessary and limit the amount of DBE used each time to a minimum.
- No eating or drinking in the work area: DBE can be easily absorbed through the skin and respiratory tract. Absolutely do not eat, drink, smoke, or apply makeup in the work area to avoid accidentally ingesting DBE.
- Wash hands frequently: Wash hands with soap and clean water after contact with DBE and before eating or drinking.
- Training for workers: Provide a comprehensive training program on the hazards of DBE, preventive measures, and how to use personal protective equipment (PPE) correctly.
Periodic health monitoring:
Workers regularly exposed to DBE should undergo periodic health monitoring to promptly detect any abnormal signs. Blood and urine tests can help check for the presence of DBE in the body.
- By strictly implementing the measures mentioned above, businesses can significantly reduce the effects of DBE on worker health, creating a safer working environment.
Occupational safety training: Workers need to be trained and educated about the risks and safety measures when working with this type of chemical. This training should be provided periodically and regularly to ensure understanding and proper compliance with safety rules.
Periodically organize workplace environment monitoring in factories and enterprises, collect and analyze factors harmful to workers, thereby adjusting to reduce hazard levels to prevent occupational diseases for them.
7. Nationwide Workplace Environment Monitoring Center
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