Pyrazoxon (C₈H₁₅N₂O₄P) is a chemical that can seriously affect the health of workers in manufacturing plants. This article will explore the impact of pyrazoxon on the body, the potential risks, and how to protect your health when exposed to this hazardous substance.
1. What is Pyrazoxon?
Pyrazoxon, with the chemical formula C₈H₁₅N₂O₄P, is an organophosphate compound primarily used in agriculture and chemical-related manufacturing plants. This chemical has a complex structure with a phosphorus (P) group combined with amine and ether groups, forming a stable yet highly toxic structure.
With the formula C₈H₁₅N₂O₄P, pyrazoxon combines carbon, hydrogen, nitrogen, oxygen, and phosphorus to form a molecule that can have a powerful effect on the nervous system. This substance acts by inhibiting the enzyme cholinesterase, an important enzyme in regulating the activity of nerve signals. When this enzyme is inhibited, nerve signals cannot be transmitted effectively, leading to symptoms of poisoning, including convulsions, respiratory depression, and even death if exposed to high levels.
Pyrazoxon is not only known for protecting crops from pests but is also a substance that needs to be carefully managed in work environments. When working in manufacturing plants that use pyrazoxon, workers can face serious health risks if safety measures are not followed during their work.
| No. | Chemical Name in Vietnamese | Chemical Name in English | HS Code | CAS Number | Chemical Formula |
| 1. | Pyrazoxon | Pyrazoxon | 29331900 | 108-34-9 | C8H15N2O4P |
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2. Where does Pyrazoxon originate from in the production process?
During the production process, pyrazoxon is mainly generated as a by-product or in chemical reactions when other organophosphate compounds are used. The production process involving the synthesis of crop protection substances or agrochemical preparations containing pyrazoxon will create a small amount of this chemical in the air and the work environment.
In addition, in manufacturing plants related to pyrazoxon, the use and handling of phosphorus-containing compounds or similar chemicals can also produce pyrazoxon as a by-product. Stages such as mixing, formulating, or packaging these chemicals can all be sources of pyrazoxon. This leads to the dispersion of pyrazoxon particles into the air, increasing the potential for worker exposure to this hazardous chemical throughout the work process.

3. Industries that use Pyrazoxon in production
Industries related to the production and use of chemicals in agriculture are places where pyrazoxon may be used. This substance is often found in pesticide manufacturing plants, where pyrazoxon is used to create products for killing insects or protecting crops from pests.
In addition, in the chemical industries, pyrazoxon can also be used in the production processes of organophosphate-containing preparations. Industrial detergent manufacturing plants or consumer product factories may contain pyrazoxon as a minor component in the process of making these products.
Industries related to pest control or agricultural chemical research may also come into contact with pyrazoxon in laboratories or production areas. These places often use pyrazoxon in tests to study the effectiveness of chemicals in killing insects or protecting crops.
4. How does Pyrazoxon affect workers?
When workers are exposed to pyrazoxon in the workplace, this substance can cause serious health effects. Pyrazoxon is an inhibitor of the enzyme cholinesterase, an important enzyme in regulating neurotransmission. When this enzyme is inhibited, nerve signals cannot be transmitted correctly, leading to an accumulation of acetylcholine in the nerve synapses, causing a state of neurotoxicity.
Workers may experience symptoms ranging from mild to severe when exposed to pyrazoxon. Initial signs may include headache, dizziness, fatigue, and nausea. With prolonged exposure or at high concentrations, pyrazoxon can cause more serious problems such as difficulty breathing, seizures, cardiac arrhythmias, and even coma. If not treated promptly, pyrazoxon poisoning can be fatal.
People working in pesticide manufacturing plants or in environments where pyrazoxon is used are at high risk of health problems, especially when proper occupational safety measures are not followed.
5. Permissible safe concentration of Pyrazoxon for human exposure
The permissible safe concentration of pyrazoxon for human exposure is regulated by international health and occupational safety organizations, such as the World Health Organization (WHO) and the Occupational Safety and Health Administration (OSHA). This safety level is mainly based on studies of the toxicity and long-term effects of the substance on human health. These studies help to determine the concentration level of pyrazoxon that humans can be exposed to without facing the risk of poisoning or serious harm.
Typically, permissible safety limits are calculated based on the level of exposure in the work environment, where the concentration of pyrazoxon in the air must not exceed a certain level. These indicators are usually measured in micrograms of pyrazoxon per cubic meter of air (µg/m³), and the recommended long-term exposure limit is the lowest concentration that can cause health effects. If the pyrazoxon concentration exceeds this limit, occupational protection measures, such as respirators or ventilation systems, must be applied to minimize the risk to workers.
This concentration level also depends on many factors, including the duration of exposure, the mode of exposure (inhalation, skin contact, or ingestion), as well as the protective capability of the occupational safety equipment used by the worker.

On a basic level, if working in an industrial environment, adhering to safety standards and limiting exposure to Pyrazoxon is important. Organizations like the Occupational Safety and Health Administration (OSHA) in the United States provide guidelines and safety principles to protect workers from the negative impacts of chemical substances.
6. Measures to minimize the health effects of Pyrazoxon on workers
To minimize the health effects of pyrazoxon on workers, it is necessary to apply a series of protective and safety control measures in the work environment. One of the most important measures is to improve the ventilation system in production areas, which helps to reduce the concentration of the chemical in the air. Good ventilation not only helps to reduce the amount of pyrazoxon in the air but also makes the work environment safer for workers.
In addition, the use of personal protective equipment such as respirators, protective gloves, and specialized clothing is essential. This equipment helps to prevent pyrazoxon from coming into direct contact with the skin or respiratory tract of workers. In areas with high concentrations of pyrazoxon, the use of a supplied-air respirator or a negative pressure ventilation system can also help protect workers from exposure to this chemical.
Occupational safety training and education also play an important role in reducing the risk of health effects. Workers need to be equipped with knowledge about the risks associated with pyrazoxon, how to recognize symptoms of poisoning, and the necessary first aid measures in case of an incident. In addition, practicing personal hygiene after a work shift, such as showering and changing clothes immediately, also helps to minimize the risk of exposure.
Finally, regular check-ups and health monitoring of workers are also very important. Periodic tests to detect signs of pyrazoxon poisoning will help to detect health problems early and allow for timely intervention.
Occupational safety training: Workers need to be trained and educated on the risks and safety measures when working with this type of chemical. This training should be provided periodically and regularly to ensure understanding and proper compliance with safety rules.
Periodically organize occupational environment monitoring in factories and enterprises, collect and analyze factors harmful to workers, thereby adjusting to reduce the level of hazard to prevent occupational diseases for them.
7. National Occupational Environment Monitoring Center
Nam Viet’s Occupational Environment Monitoring Center is a professional unit for monitoring and measuring the quality of the working environment across all provinces in Vietnam. With a team of experienced monitoring specialists, the center uses modern measuring equipment, ensuring accuracy and reliability.
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In addition to providing monitoring services, the center also assists clients in planning, handling, and tracking occupational environment issues. With the motto “the customer is the center,” the center focuses on customer satisfaction, meets all customer needs, and is committed to providing the best solutions for businesses.
With investment in technology, engineering, and human resources, Nam Viet’s monitoring center has become one of the reputable units in the field of occupational environment monitoring in Ho Chi Minh City with the following objectives:
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- With a team of experienced Masters and Engineers with a desire to protect the environment and benefit businesses.

- With the Nam Viet Environmental Monitoring team, your company will receive professional service from experts in the monitoring field. You will also get the best cost incentives.
8. Quotation for Occupational Environment Monitoring
To help businesses carry out occupational environment monitoring professionally and effectively, Nam Viet offers our customers a quality and reasonably priced quotation table for occupational environment monitoring services.
- Our quotation table provides detailed information about the prices of the monitoring services we offer. This includes costs related to travel, measurement, analysis, and reporting of results. Customers can be completely assured of the accuracy and reliability of the monitoring result reports we provide.
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