Hexafluoro phosphoric acid (HPF6) is a hazardous chemical used in many industries. However, long-term exposure can cause serious health effects for workers. This article will provide information on the harmful effects and how to protect your health when working with HPF6.
1. What is Hexafluoro phosphoric acid?
HPF6 is an inorganic acid with a chemical formula consisting of one phosphorus atom bonded to six fluorine atoms. It is an extremely strong acid, known for its volatility and strong reactivity with other compounds. The molecular structure of HPF6 is very specific, with phosphorus (P) at the center and fluorine (F) atoms attached around it, creating a very stable molecular structure under normal conditions.
This acid is primarily used in industries such as electronics, battery manufacturing, and in chemical processes that require a strong acidic environment. HPF6 can also dissolve many metals and other materials, making it a useful catalyst in industrial chemical reactions.
| No. | Chemical Name in Vietnamese | Chemical Name in English | HS Code | CAS Number | Chemical Formula |
| 1. | Axit hexaflo photphoric | Hexafluoro phosphoric acid | 28111990 | 16940-81-1 | HPF6 |
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2. Where does Hexafluoro phosphoric acid originate from in the production process?
During production, HPF6 is often generated from reactions between phosphoric acid and fluorine compounds such as hydrofluoric acid (HF). This process typically occurs in electronics manufacturing plants, especially in the production of electronic components or in the production of electrolytic solutions used in lithium batteries. HPF6 can also be created in the chemical industry, where ion exchange reactions occur between phosphorus- and fluorine-containing compounds.
In addition, HPF6 can also appear in the synthesis processes of organic compounds or in the manufacturing of catalysts.

3. Industries that use Hexafluoro phosphoric acid in production
HPF6 is mainly used in industries that require a strong acidic environment and special catalysts. In electronics manufacturing, this acid is used to fabricate electronic components, especially in the production process of lithium batteries, where HPF6 helps create high-performance electrolytic solutions. These processes require special chemicals to optimize battery efficiency while protecting the system’s components from wear and damage.
In addition, HPF6 is also used in the chemical industry to synthesize organic compounds and as a catalyst in chemical reactions. It also plays an important role in the production of polymers or special materials that require high durability and corrosion resistance. Besides, in the field of metal processing, this acid can be used to clean and fabricate special metal materials.
In some cases, HPF6 is also used in the production of electrolytic solutions for advanced technologies, such as in the research and development of solar battery systems or other renewable energy applications.
4. How does Hexafluoro phosphoric acid affect workers?
When exposed to HPF6, workers may experience negative health effects due to the strong corrosive nature of this acid. Inhaling HPF6 vapor can cause severe respiratory irritation, leading to coughing, shortness of breath, or even pneumonia. If it comes into direct contact with the skin or eyes, this acid can cause burns, tissue damage, and cell destruction, and may even lead to long-lasting ulcers. The risk of these effects is particularly high in work environments that are not equipped with adequate protective equipment.
Furthermore, long-term exposure to HPF6 can also affect the nervous system, causing symptoms such as headaches, dizziness, fatigue, and difficulty concentrating. Some studies have suggested that prolonged exposure to fluorine-containing compounds, including HPF6, may increase the risk of bone and dental diseases, such as osteoporosis or digestive system problems.
5. Permissible safe concentration of Hexafluoro phosphoric acid for human exposure
The safe concentration of HPF6 for human exposure depends on many factors, including the duration of exposure, the method of contact (vapor, skin, eyes), and the level of personal protection. However, there is currently no specific official standard for the permissible safe concentration for exposure to this chemical. Due to the strong corrosive and toxic nature of HPF6, regulatory organizations like OSHA (the U.S. Occupational Safety and Health Administration) recommend that worker exposure to this chemical not exceed the minimum level that could pose serious health risks.
In production environments, the concentration of HPF6 in the air must be maintained below the maximum permissible limit, which is typically under 1 mg/m³, to ensure worker safety. These standards are based on limiting long-term exposure and ensuring adequate ventilation to minimize inhalation of the acid vapor.
Although there is no official standard concentration for all cases, strict safety measures must be implemented in all production processes involving HPF6.

On a basic level, when working in an industrial environment, it is important to adhere to safety standards and limit exposure to Hexafluoro phosphoric acid. Organizations like the Occupational Safety and Health Administration (OSHA) in the United States provide guidelines and safety principles to protect workers from the negative effects of chemical substances.
6. Measures to minimize the health effects of Hexafluoro phosphoric acid on workers
To minimize the health effects of HPF6 on workers, applying safety protection measures is extremely important. First, factories and production facilities need to establish a good ventilation system to ensure the concentration of HPF6 vapor in the air is always at a safe level. This helps to reduce the risk of inhaling the acid vapor, one of the main causes of respiratory irritation and health problems.
In addition, workers must be fully equipped with personal protective equipment, including respirators, corrosion-resistant gloves, safety goggles, and specialized protective clothing. This equipment helps protect workers from direct contact with HPF6 on the skin and in the eyes, thereby preventing burns or serious injuries caused by this chemical.
Besides personal protection, training and raising awareness for workers about the risks associated with HPF6 is also very important. Workers need to be trained on how to handle emergency situations involving chemical spills, including how to use protective equipment, provide first aid, and report incidents immediately.
Furthermore, production processes must strictly adhere to occupational safety standards and undergo regular inspections to detect potential hazards in a timely manner. These protective measures not only help ensure the health of workers but also contribute to maintaining a safe and efficient working environment.
Occupational safety training: Workers need to be trained and educated about the risks and safety measures when working with this type of chemical. This training should be provided periodically and regularly to ensure understanding and proper adherence to safety rules.
Periodically organize workplace environment monitoring in factories and enterprises, to collect and analyze factors harmful to workers, thereby adjusting to reduce the hazard level to prevent occupational diseases for them.
7. National Workplace Environment Monitoring Center
Nam Viet’s Workplace Environment Monitoring Center is a professional unit specializing in monitoring and measuring the quality of the working environment across all provinces in Vietnam. With a team of experienced monitoring specialists, the center uses modern measuring equipment, ensuring accuracy and reliability.
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In addition to providing monitoring services, the center also assists clients in planning, handling, and tracking workplace environment issues. With the motto “the customer is the center,” the center focuses on customer satisfaction, meets all customer needs, and is committed to providing the best solutions for businesses.
With investment in techniques, technology, and human resources, Nam Viet’s monitoring center has become one of the reputable units in the field of workplace environment monitoring in Ho Chi Minh City with the following objectives:
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8. Workplace Environment Monitoring Quotation
To help businesses carry out workplace environment monitoring professionally and effectively, Nam Viet offers our customers a quality and reasonably priced quotation for workplace environment monitoring services.
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