Nicotine is a synthetic stimulant found in the leaves of the tobacco plant and is commonly used in the production of tobacco products.
Although nicotine is not carcinogenic or excessively harmful on its own, it is highly addictive and can cause extremely harmful effects on the human body.
1. What is Occupational Nicotine Poisoning?
Occupational nicotine poisoning is caused by long-term exposure to nicotine during work. Nicotine is a natural neurostimulant found in tobacco, widely used in the production of tobacco and electronic cigarettes.

2. Occupations at Risk of Nicotine Poisoning
Occupations at risk of exposure to nicotine and occupational nicotine poisoning include:
- Workers in the tobacco and e-cigarette manufacturing industry exposed to nicotine during processes such as stripping leaves, drying, sifting, treating materials, cutting fibers, rolling cigarettes, packaging, etc.
- Jobs involving harvesting, packing, or transporting tobacco products.
- Healthcare personnel who may be exposed to nicotine through the treatment of tobacco-related diseases such as chronic obstructive pulmonary disease (COPD) or lung cancer.
- Workers handling waste or incinerating tobacco factory waste.
- Other occupations related to tobacco use, such as bar staff, waitstaff, and truck drivers, may also have nicotine exposure risk.

3. Mechanism and Causes of Nicotine Poisoning
Nicotine can enter the body through multiple routes: respiratory (rapid absorption, a major route in occupational poisoning), digestive (usually causing acute poisoning via accidents), skin, and eye mucosa.
The mechanism of nicotine poisoning involves its effects on nerve cells and bodily systems. Nicotine stimulates nerve cells, triggering chemical reactions in the brain and body, increasing dopamine production—a neurotransmitter associated with feelings of satisfaction and happiness.
Once in the body, nicotine quickly enters the bloodstream and reaches the brain, affecting neurons. About half of the nicotine is metabolized by the liver within approximately 2 hours of entry.

4. Symptoms of Nicotine Poisoning
Symptoms vary depending on exposure level and duration, but common signs include:
- Dizziness, severe headache, pale complexion.
- Nausea, vomiting, abdominal pain, diarrhea.
- Salivation, cold sweats.
- Rapid heartbeat, increased blood pressure, chest pain.
- Visual and auditory disturbances.
- Eyelid twitching, hand tremors, cramps, joint pain.

5. Hazards of Occupational Nicotine Poisoning
Occupational nicotine poisoning can seriously affect workers’ health, including:
- Frequent exposure may reduce lung capacity, causing chronic bronchitis, emphysema, and reduced pulmonary ventilation.
- Gastrointestinal issues: stomach ulcers, indigestion, nausea, vomiting, loss of appetite, diarrhea, heartburn, epigastric pain.
- Nervous system disorders: dizziness, headache, insomnia, anxiety, stress, memory impairment, hearing loss, tremors, joint pain.
- Increased risk of heart disease and stroke, arrhythmias, blood pressure fluctuations.
- Potential liver and kidney damage.
- Mucosal irritation: dry throat, mouth inflammation, conjunctivitis (watery eyes, eye pain, reduced vision).

6. Protective Equipment to Prevent Nicotine Poisoning
To prevent nicotine poisoning, workers should use proper personal protective equipment (PPE), including:
- Respiratory masks to protect the respiratory tract.
- Protective gloves to prevent hand contact with nicotine.
- Protective clothing to prevent direct nicotine exposure.
- Safety goggles to protect eyes from nicotine and dust.
- Safety boots to protect feet.
- Protective suits to safeguard the whole body.
Proper training on PPE usage and maintenance is essential, with periodic replacement to ensure effectiveness and safety.
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7. Compensation for Workers with Nicotine Poisoning
In Vietnam, under the Social Insurance Law, workers suffering from occupational nicotine poisoning are entitled to:
- Healthcare coverage for treatment and care related to nicotine poisoning.
- Social insurance benefits according to the law.
- Employer compensation if unsafe materials or equipment caused the poisoning.
- Occupational disease assessment to claim insurance and support.
Workers must prove the poisoning was work-related to claim benefits.
8. Treatment for Occupational Nicotine Poisoning
Treatment depends on severity and symptoms:
- Stop or reduce exposure; use PPE such as masks, gloves, goggles, and protective clothing.
- Use medications as prescribed (painkillers, anti-inflammatories, gastric medications).
- Maintain proper nutrition, exercise, and rest for recovery.
- Vitamin and mineral supplementation to aid recovery.
- Psychological support to address stress, anxiety, and depression.
- Severe cases may require hospital treatment under medical supervision.
9. Prevention of Occupational Nicotine Poisoning
Prevention measures include:
- Regular ventilation and dust extraction to reduce nicotine and tobacco dust concentrations.
- Cleaning factory areas (walls, ceilings, floors) with wet spraying or vacuuming.
- Wearing PPE: gloves, masks, protective clothing, boots.
- Personal hygiene during and after shifts: change clothes, shower, especially for women.
- Report suspected poisoning symptoms promptly to health authorities.
- Select healthy workers without chronic respiratory, cardiovascular, or skin conditions for nicotine exposure tasks.
- Periodic health checks to reassign duties or treat affected workers.
- Conduct workplace environmental monitoring and report results regularly to improve safety conditions.
10. Employer Responsibilities in Preventing Nicotine Poisoning
Employer responsibilities include:
- Providing information on nicotine hazards and other toxins in tobacco to employees.
- Providing PPE such as masks, gloves, clothing, and goggles to reduce exposure risks.
- Implementing preventive measures: improving ventilation, maintaining cleanliness, minimizing dust and toxins.
- Conducting regular health checks to detect early signs of nicotine poisoning.
- Providing training and updates on occupational health and safety regulations.
Employers must ensure a safe and healthy working environment and take preventive measures to protect workers’ health.
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