Bitertanol (C20H23N3O2) is a chemical widely used in manufacturing plants. However, long-term exposure to this substance can cause harmful effects on the health of workers. This article will explore in detail the health effects of Bitertanol and protective measures.
1. What is Bitertanol?
Bitertanol, with the chemical formula C20H23N3O2, is a compound belonging to the triazole and biphenyl groups, used primarily as a fungicide. This compound exists as a mixture of four isomers, including (1R,2R)-bitertanol, (1S,2S)-bitertanol, (1R,2S)-bitertanol, and (1S,2R)-bitertanol.
Bitertanol is a colorless solid, sparingly soluble in water but readily soluble in organic solvents such as acetone, dichloromethane, ethyl acetate, and dimethyl sulfoxide. It has a melting point of about 136–137 °C and an estimated boiling point of about 300 °C, at which point the substance decomposes.
With a molecular weight of approximately 337.42 g/mol, bitertanol has a molecular structure consisting of a triazole group linked to a 4-phenylphenoxy group and a 3,3-dimethylbutanol group.
To synthesize bitertanol, a series of chemical reactions are typically performed, starting from 3,3-dimethyl-2-butanone, and going through steps such as chlorination, nucleophilic substitution, bromination, and ketone reduction with hydrogen.
Thanks to its special structure and chemical properties, bitertanol has been widely applied in agriculture as a fungicide, helping to control many types of diseases on crops.
| No. | Chemical Name in Vietnamese | Chemical Name in English | HS Code | CAS Number | Chemical Formula |
| 1. | Bitertanol | Bitertanol | 29339990 | 55179-31-2 | C20H23N3O2 |
See more: chemical safety training service according to Decree 113/2017/ND-CP
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2. Where does Bitertanol originate from in the production process?
During production, the source of Bitertanol primarily comes from plants that process and manufacture plant protection products. It is a compound synthesized through complex chemical reactions, mainly from chemical raw materials such as 3,3-dimethyl-2-butanone, halogen compounds, and special catalysts. When these raw materials react with each other under certain conditions, Bitertanol is created in the form of isomers with the chemical formula C20H23N3O2.
This production process usually takes place in laboratories or specialized production areas of chemical plants, where chemical processes such as chlorination, bromination, and ketone reduction are carefully carried out to ensure the quality and purity of the final product. In this production environment, the chemicals and reacting compounds can generate gases and chemical substances, which can thus create a source of Bitertanol.

3. Industries that use Bitertanol in production
The industries that use Bitertanol in production are mainly related to agriculture and the chemical industry. In agriculture, this compound is widely used in the production of plant protection products, especially fungicides. Agricultural processing plants, fertilizer production facilities, or large-scale farming operations often use Bitertanol to protect crops from fungal diseases, such as mildew and diseases on rice, corn, vegetables, and other crops.
Besides the agricultural sector, some chemical industries also use Bitertanol in the production process of specialized chemicals. Facilities that produce plant protection products and related agricultural chemicals need to use Bitertanol to create highly effective products for preventing and controlling fungal diseases. In this industrial environment, Bitertanol is used as part of synthetic fungicide products, playing an important role in controlling agents that are harmful to crops.
4. How does Bitertanol affect workers?
When workers are exposed to Bitertanol during their work, health effects can occur depending on the level and duration of exposure to this chemical. This chemical can enter the body through the skin, inhalation of dust, or vapors from solutions containing Bitertanol during production. Without proper protective measures, workers may experience negative health effects.
In cases of prolonged or high-concentration exposure, symptoms can appear in various organs of the body. Initial symptoms may include skin irritation, red rashes, or itching, especially upon direct contact with solutions containing Bitertanol. Inhaling vapors or dust of this substance can cause respiratory problems, such as coughing, shortness of breath, or symptoms similar to rhinitis or bronchitis.
Furthermore, long-term exposure to Bitertanol can also affect the nervous system and other functions in the body, leading to a decline in the overall health of the worker. Some studies also indicate that, if not strictly controlled, continuous exposure to Bitertanol can lead to serious health problems, including liver or kidney dysfunction.
5. Permissible safe concentration of Bitertanol for human exposure
The safe concentration of Bitertanol for human exposure is determined based on the standards and guidelines of international health and quality management organizations. However, detailed information about specific concentration limits of Bitertanol in the workplace or for daily exposure is not provided in current sources. To ensure safety, it is necessary to adhere to the guidelines for the use of and exposure to plant protection products, including Bitertanol.

On a basic level, if working in an industrial environment, it is important to comply with safety standards and limit exposure to Bitertanol. Organizations such as the Occupational Safety and Health Administration (OSHA) in the United States provide guidelines and safety principles to protect workers from the negative effects of chemical substances.
6. Measures to minimize the effects of Bitertanol on worker health
To minimize the effects of Bitertanol on worker health, protective measures and risk control must be strictly implemented during the production process. One of the important measures is to ensure a well-ventilated work environment, with an effective ventilation system to reduce the concentration of Bitertanol vapor or dust in the air. Factories should be equipped with dust extraction systems or cooling systems to prevent the spread of the chemical in the workspace.
In addition, workers must be fully equipped with personal protective equipment, including gloves, chemical-resistant respirators, safety goggles, and protective clothing. The use of this equipment will help prevent direct contact with Bitertanol through the skin or respiratory tract. At the same time, personal hygiene measures are also very important; workers must wash their hands and change their protective clothing after each shift to avoid long-term contact with the chemical.
Production facilities should also organize regular training courses to raise awareness and skills for workers in the safe use, storage, and handling of Bitertanol. In addition, regular health monitoring for workers is also necessary to detect early symptoms or signs of illness related to exposure to this chemical. These measures help to minimize the risk of harm to the health of workers in an environment where Bitertanol is used.
Occupational safety training: Workers need to be trained and educated about the risks and safety measures when working with this type of chemical. This training should be provided periodically and regularly to ensure understanding and proper adherence to safety rules.
Periodically organize workplace environmental monitoring in factories and enterprises, collecting and analyzing factors harmful to workers, and from there, adjusting to reduce the level of harm to prevent occupational diseases for them.
7. National Workplace Environmental Monitoring Center
Nam Viet’s Workplace Environmental Monitoring Center is a professional unit for monitoring and measuring the quality of the working environment across all provinces in Vietnam. With a team of experienced monitoring specialists, the center uses modern measuring equipment, ensuring accuracy and reliability.
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In addition to providing monitoring services, the center also supports customers in planning, handling, and tracking workplace environmental issues. With the motto “the customer is the center,” the center is concerned with customer satisfaction, meeting all customer needs, and is committed to providing the best solutions for businesses.
With investment in technology, engineering, and human resources, Nam Viet’s monitoring center has become one of the reputable units in the field of workplace environmental monitoring in Ho Chi Minh City with the following objectives:
- We always value our brand reputation and the quality of our products and services.
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- Along with a team of experienced Masters and Engineers with a desire to protect the environment and benefit businesses.

- Coming to the Nam Viet Environmental Monitoring team, your company will receive professional service with experts in the field of monitoring. At the same time, you will get the best cost incentives.
8. Quotation for Workplace Environmental Monitoring
To help businesses carry out workplace environmental monitoring in a professional and effective manner, Nam Viet provides our customers with a quality and reasonably priced quotation for workplace environmental monitoring services.
- Our quotation provides detailed information on the prices of the monitoring services we offer. This includes costs related to travel, measurement, analysis, and reporting of results. You can be completely confident in the accuracy and reliability of the monitoring result reports we provide.
- We are committed to always offering the most competitive and reasonable prices on the market, and we are also always ready to provide consultation and answer any questions about monitoring services in the quickest and most professional manner.
- With Nam Viet’s quotation, you can easily choose the service packages that suit your needs. We are committed to bringing you the highest satisfaction with our professional service quality.

