n-Butyl acetate (C6H12O2) is a chemical compound commonly used in manufacturing industries. However, long-term exposure to this chemical can cause serious health effects for workers. This article will explore the impacts of n-Butyl acetate on health when working in a factory environment.
1. What is n-Butyl acetate?
n-Butyl acetate, with the chemical formula C6H12O2, is an organic ester formed from the reaction between acetic acid and butanol. This compound exists as a clear, colorless liquid with a sweet, fruity odor, often compared to the smell of bananas or apples. n-Butyl acetate has a boiling point of about 126°C and a melting point of -74°C.
With the molecular formula C6H12O2, n-Butyl acetate is one of the isomers of butyl acetate, which includes isobutyl acetate, sec-butyl acetate, and tert-butyl acetate. This compound is not only widely used in industries such as paints, adhesives, cleaning agents, and plastic production but also appears in many types of fruits, contributing to their characteristic flavors.
| No. | Chemical Name in Vietnamese | Chemical Name in English | HS Code | CAS Number | Chemical Formula |
| 1. | Butyl axetat | n-Butyl acetate | 29153300 | 123-86-4 | C6H12O2 |
See more services: Chemical safety training according to Decree 113/2017/ND-CP
REGISTER FOR CHEMICAL OCCUPATIONAL SAFETY TRAINING ACCORDING TO DECREE 113
2. Where does n-Butyl acetate originate from in the production process?
During the production process, n-Butyl acetate is primarily created through the esterification reaction between acetic acid and butanol. This is a chemical reaction in which the hydroxyl group (-OH) of butanol combines with the carboxyl group (-COOH) of acetic acid, releasing water and forming n-Butyl acetate. This reaction takes place in the presence of an acid catalyst, such as sulfuric acid, which helps to speed up the reaction process and yield the product effectively.
Additionally, n-Butyl acetate can also be generated in some other industrial production processes, such as in factories that produce paints, cleaning agents, or plastics. In these environments, n-Butyl acetate may arise from side reactions or from the use of compounds containing butyl ester groups. Volatile substances in the work environment can create n-Butyl acetate and some of its isomers, thereby coming into contact with workers and other materials during the production process.

3. Industries that use n-Butyl acetate in production
N-Butyl acetate is widely used in many different industries due to its properties, such as good solubility in many solvents and a pleasant aroma. In the paint industry, this chemical is an important component in formulating various types of paints, especially surface coatings, art paints, and automotive paints, helping to improve the smoothness and durability of the product. Additionally, n-Butyl acetate also acts as a solvent in detergent formulations, helping to clean and remove grease effectively.
In the plastics manufacturing industry, this compound is used as a solvent in the production of various types of plastics and synthetic rubber. It helps improve the solubility of additives and increases the flexibility of plastic materials, while also reducing viscosity during the manufacturing process. Besides that, n-Butyl acetate is also used in the printing industry, especially in ink production, helping the ink to adhere easily to surfaces and dry quickly.
This chemical also appears in the food processing industry, where it is used as a flavoring agent in products such as candy, cakes, and soft drinks, thanks to its natural aroma. Other industries such as the production of adhesives, cosmetics, and dyes also utilize the properties of n-Butyl acetate to enhance the quality of the final product.
4. How does n-Butyl acetate affect workers?
When exposed to n-Butyl acetate over a long period in the workplace, workers may experience several negative health effects. This compound can enter the body through inhalation, skin contact, or ingestion. In the air, n-Butyl acetate evaporates easily, and when high concentrations of this substance are inhaled, workers may experience symptoms such as dizziness, headache, nausea, and fatigue. If exposure is prolonged, it can cause damage to the nervous system, especially symptoms like visual disturbances and impaired concentration.
N-Butyl acetate can also cause skin and eye irritation. When in direct contact with the skin, this compound can cause redness, itching, and dermatitis. If it gets in the eyes, it can cause a burning sensation, redness, and in severe cases, may damage the cornea. Furthermore, in a work environment with n-Butyl acetate, the risk of acute poisoning is quite high if appropriate protective measures are not taken.
One of the more serious effects that workers may face is the impact on the respiratory system. Inhaling these chemical vapors for a long time can lead to respiratory diseases, such as chronic bronchitis or lung problems. In addition, n-Butyl acetate can also increase the body’s sensitivity to allergens, exacerbating existing allergic conditions.
5. Permissible safe concentration of n-Butyl acetate for human exposure
When working in an environment with n-Butyl acetate, it is crucial to adhere to exposure concentration limits to ensure health and occupational safety. Professional organizations have issued recommendations for the maximum permissible exposure levels for this compound. Specifically, the American Conference of Governmental Industrial Hygienists (ACGIH) recommends a time-weighted average (TWA) exposure limit of 50 parts per million (ppm) and a short-term exposure limit (STEL) of 150 ppm. The TWA represents the average concentration level that a worker can be exposed to over an 8-hour workday, while the STEL is the maximum concentration allowed for a short period, typically 15 minutes.

At a basic level, when working in an industrial environment, it is important to adhere to safety standards and limit exposure to Butyl acetate. Organizations such as the Occupational Safety and Health Administration (OSHA) in the United States provide guidelines and safety principles to protect workers from the negative impacts of chemical substances.
6. Measures to minimize the effects of n-Butyl acetate on worker health
To minimize the health effects of n-Butyl acetate on workers, control and protection measures must be strictly implemented in the work environment. One of the most effective methods is to improve the ventilation system in areas where this chemical is used. Ensuring good air circulation helps to reduce the concentration of chemical vapors in the air, thereby limiting workers’ exposure to n-Butyl acetate.
In addition, using personal protective equipment (PPE) is a necessary measure to protect workers from direct contact with the chemical. Workers should be equipped with chemical-resistant respirators, protective gloves, and safety goggles to minimize the chance of n-Butyl acetate coming into contact with the skin, eyes, and respiratory tract. The use of specialized protective clothing also helps to reduce the risk of skin absorption when working in areas with high concentrations of this chemical.
Furthermore, factories and workshops need to establish safety procedures, including regular monitoring and testing of n-Butyl acetate levels in the workplace air. Providing training for workers on safety measures when handling chemicals and creating strict regulations regarding work duration in environments containing n-Butyl acetate are also important steps to minimize risks. Implementing timely first-aid measures in case of an incident or overexposure is also a critical factor in protecting workers’ health.
Occupational safety training: Workers need to be trained and educated about the risks and safety measures when working with this type of chemical. This training should be provided periodically and regularly to ensure understanding and proper compliance with safety rules.
Periodically organize workplace environment monitoring in factories and enterprises, collect and analyze factors harmful to workers, and then adjust to reduce the hazard level to prevent occupational diseases for them.
7. Nationwide Workplace Environment Monitoring Center
Nam Viet’s workplace environment monitoring center is a professional unit specializing in the supervision and measurement of workplace environmental quality across all provinces in Vietnam. With a team of experienced monitoring specialists, the center uses modern measuring equipment, ensuring accuracy and reliability.
REGISTER FOR WORKPLACE ENVIRONMENT MONITORING SERVICES
In addition to providing monitoring services, the center also supports clients in planning, processing, and tracking workplace environment issues. With the motto “the customer is the center,” the center focuses on customer satisfaction, meeting all of their needs, and is committed to providing the best solutions for businesses.
With investments in technology, techniques, and personnel, Nam Viet’s monitoring center has become one of the reputable units in the field of workplace environment monitoring in Ho Chi Minh City with the following objectives:
- We always value our brand reputation and the quality of our products and services.
- We provide our customers with the best and most suitable solutions possible.
- Along with a team of experienced Masters and Engineers with a desire to protect the environment and benefit businesses.

- With Nam Viet’s Environmental Monitoring team, your company will receive professional service from experts in the monitoring field. At the same time, you will get the best offers on costs.
8. Quotation for workplace environment monitoring
To help businesses conduct workplace environment monitoring professionally and effectively, Nam Viet offers our customers a quality and reasonably priced quotation for workplace environment monitoring services.
- Our quotation provides detailed information on the prices of the monitoring services we offer. This includes costs related to travel, measurement, analysis, and reporting of results. Customers can be completely assured of the accuracy and reliability of the monitoring result reports we provide.
- We are committed to always offering the most competitive and reasonable prices on the market, and we are always ready to provide consultation and answer any questions about our monitoring services quickly and professionally.
- With Nam Viet’s quotation, customers can easily choose service packages that suit their needs. We are committed to bringing our customers the highest satisfaction with professional quality service.

