The impact of Chloronitro aniline (C6H5O2N2Cl) on the health of workers in manufacturing plants is the main focus of this article. Learn about the risks and how to cope to protect your health!
1. What is Chloronitro aniline?
Chloronitro aniline is a chemical compound with the chemical formula C6H5O2N2Cl. Known as an organic compound, it can exist in the form of white crystals. This formula indicates that this compound includes a phenyl group (C6H5), a nitro group (NO2), and a chlorine atom (Cl) attached to an aniline molecule.
Aniline is an organic compound with the chemical formula C6H5NH2, in which an amino group (NH2) is attached to a phenyl group. When a chlorine atom (Cl) is substituted at the ortho or para position of the amino group on the aniline molecule, chloronitro aniline is obtained. The formula C6H5O2N2Cl is the result of substituting a chlorine atom at the ortho or para position of the amino group on the aniline molecule.
Chloronitro aniline is a substance used in the chemical industry, especially in the production processes of dyes and other chemicals. The presence of the nitro group (NO2) and the chlorine group (Cl) in the chloronitro aniline molecule can have potential impacts on human health when exposed to this compound in the work environment.
| No. | Chemical Name (Vietnamese) | Chemical Name (English) | HS Code | CAS Number | Chemical Formula |
| 1. | Clo nitroanilin | Chloronitro aniline | 29214200 | 121-87-9 | C6H5O2N2Cl |
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2.Where does Chloronitro aniline originate from in the production process?
Chloronitro aniline is a substance generated during the production of chemicals and industrial products such as dyes and pharmaceuticals. Typically, chloronitro aniline is synthesized from chemical reactions on the base material, aniline. The production process involves reacting aniline with hydrochloric acid (HCl) and nitrate, leading to the substitution of a chlorine atom at the ortho or para position of the amino group on the aniline molecule.
In manufacturing plants, this process often occurs in special chemical reactions carried out under controlled conditions and with the intervention of catalysts. Chloronitro aniline can be produced through a chemical synthesis process on an industrial production line.
Due to the complex chemical nature of this production process, various types of waste and by-products can also be generated during the production of chloronitro aniline. Waste management and control of the production process are very important to ensure worker safety and protect the environment.

3. Industries that use Chloronitro aniline in production
Chloronitro aniline is a chemical compound used primarily in the dye and pharmaceutical manufacturing industries. In the dye manufacturing industry, chloronitro aniline is used as a primary raw material to synthesize colorants and other organic compounds. These dye products are then used in the textile and printing industries to create fabric products with diverse colors.
In addition, chloronitro aniline may also be used in pharmaceutical production, especially in the synthesis of active ingredients used in medicines. However, the use of chloronitro aniline in the pharmaceutical industry is often strictly controlled due to the toxicity and danger of this compound to human health.
Besides the industries above, chloronitro aniline may also be used in some other fields such as synthetic chemical production and the production of special organic compounds. The use of chloronitro aniline in these industries also requires strict safety and control measures to ensure safety for workers and the production environment.
4. How does Chloronitro aniline affect workers?
Chloronitro aniline is a toxic substance that can cause many negative impacts on worker health if exposed directly or indirectly during the production process. The severity of the effects depends on many factors, such as:
- Concentration and duration of exposure: Inhaling Chloronitro aniline vapor or skin contact for a long time or at high concentrations will cause more serious effects.
- Route of exposure: Chloronitro aniline can enter the body through the respiratory tract, digestive tract, or skin. Inhalation of vapor is the most common route of exposure in the production environment.
- Individual health status: People with pre-existing conditions of the respiratory tract, liver, kidneys, or central nervous system may be more sensitive to the effects of Chloronitro aniline.
Here are some of the effects of Chloronitro aniline on worker health:
- Acute poisoning: When exposed to high concentrations of Chloronitro aniline for a short time, workers may experience symptoms such as dizziness, nausea, difficulty breathing, methemoglobinemia (a condition that makes it difficult for blood to carry oxygen to tissues). In severe cases, acute poisoning can lead to coma and death.
- Chronic poisoning: Long-term exposure to lower concentrations of Chloronitro aniline can also cause health problems such as dermatitis, respiratory irritation, headaches, fatigue, and blood function disorders.
- Cancer risk: Some studies suggest that Chloronitro aniline may have carcinogenic potential. However, more research is needed to clearly determine this link.
To protect worker health, controlling the concentration of Chloronitro aniline in the production environment according to occupational safety regulations is necessary. In addition, using adequate protective equipment, implementing safe work procedures, and undergoing periodic health check-ups are important factors in helping to minimize the risk of Chloronitro aniline poisoning.
5. Permissible safe concentration of Chloronitro aniline for human exposure
Currently, there is no single international standard for the permissible concentration of Chloronitro aniline for safe exposure to workers. However, some reputable occupational safety organizations provide recommendations for Occupational Exposure Limits (OEL) such as:
- ACGIH (American Conference of Governmental Industrial Hygienists): The recommended Time-Weighted Average (TWA) exposure limit is 1 mg/m³ for 8 hours of work per day, 40 hours per week.
- NIOSH (National Institute for Occupational Safety and Health): The recommended exposure limit is 1 mg/m³ for 10 hours of work per day, 40 hours per week.
- OSHA (Occupational Safety and Health Administration): Has not set a specific exposure limit for Chloronitro aniline, but applies the general regulation for nitroaniline compounds, which is 5 mg/m³.
Note that these OEL values are only guidelines and may vary depending on the specific factors of the work environment, such as exposure duration, type of activity, and the health status of the workers.
More important than adhering to OELs is controlling the concentration of Chloronitro aniline in the production environment to the lowest possible level through engineering and administrative measures. This helps minimize the risk of poisoning for workers.
Effective control measures include:
- Ventilation (good air circulation): Maintain an effective ventilation system to remove Chloronitro aniline vapor from the work environment.
- Enclosed systems: Use enclosed equipment systems to limit the generation and leakage of Chloronitro aniline into the environment.
- Personal protective equipment: Provide workers with appropriate protective gear such as masks, gloves, and protective clothing to limit direct contact with Chloronitro aniline.
- Personal hygiene: Require workers to practice proper personal hygiene after finishing their work shift to remove substances adhering to the skin.
By combining engineering controls, administrative measures, and protective equipment, businesses can create a safe working environment for workers when exposed to Chloronitro aniline.

At a basic level, when working in an industrial environment, it is important to comply with safety standards and limit exposure to Chloronitro aniline. Organizations like the Occupational Safety and Health Administration (OSHA) in the United States provide guidelines and safety principles to protect workers from the negative impacts of chemical substances.
6. Measures to minimize the effects of Chloronitro aniline on worker health
To minimize the health effects of chloronitro aniline on workers, safety and prevention measures must be applied in the work environment. Some specific measures include:
- Use of personal protective equipment (PPE): Ensure workers are fully equipped with PPE such as masks, safety glasses, gloves, and protective clothing to protect their skin, eyes, and respiration from direct contact with chloronitro aniline.
- Training and education: Provide regular training on risks and preventive measures for employees. Ensure they understand and adhere to safety procedures and use PPE correctly during work.
- Control of exposure levels: Monitor and measure the concentration of chloronitro aniline in the work environment to ensure a safe concentration for workers. Adjust production processes and ventilation to minimize the spread of the chemical in the air.
- Waste management: Treat and dispose of chloronitro aniline waste according to environmental and occupational safety regulations. Ensure waste treatment methods are safe enough not to affect human health and the environment.
- Health investigation and monitoring: Implement periodic health monitoring programs to track the impact of chloronitro aniline on worker health. This helps detect health problems early and implement timely preventive measures.
Overall, implementing these measures will help minimize risks and protect the health of workers in production environments using chloronitro aniline. Safety procedures and strict compliance with regulations are very important to ensure a safe and healthy work environment.
Occupational safety training: Workers need to be trained and educated about the risks and safety measures when working with this type of chemical. This training should be provided periodically and regularly to ensure understanding and proper compliance with safety rules.
Periodically organize workplace environment monitoring in factories and enterprises, collect and analyze factors harmful to workers, thereby adjusting to reduce hazard levels to prevent occupational diseases for them.
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