Diphacinone (C23H16O3) is a chemical used in production, but it poses a serious potential risk to the health of workers. This article will explore the impact of Diphacinone on the health of workers in a manufacturing plant environment, helping to identify risks and preventive measures.
1. What is Diphacinone?
Diphacinone, with the chemical formula C23H16O3, is a chemical compound belonging to the coumarin group, primarily used in the manufacturing of rodenticides. It is a long-acting poison that helps prevent the growth of rats in industrial and agricultural environments. Diphacinone works by inhibiting the enzyme vitamin K epoxide reductase, thereby preventing the synthesis of blood clotting factors, which leads to the blood being unable to clot, causing internal bleeding in the poisoned organism.
With the formula C23H16O3, Diphacinone has a chemical structure that includes three benzene rings, a coumarin ring, and a hydroxyl group (-OH) at a specific position in the molecule. This characteristic contributes to the toxic properties of the compound when it comes into contact with organisms that have a circulatory system. Although Diphacinone is very effective at killing rats, it also poses many dangers to human and animal health if not used correctly.
In manufacturing plants where Diphacinone is used for pest control, workers may be exposed to this chemical, leading to adverse health effects if appropriate protective measures are not in place.
| No. | Chemical Name in Vietnamese | Chemical Name in English | HS Code | CAS Number | Chemical Formula |
| 1. | Diphacinon | Diphacinone | 29143900 | 82-66-6 | C23H16O3 |
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2. Where does Diphacinone originate from in the production process?
During the production process, the source of Diphacinone primarily comes from its use in rodenticides and pest control products. Diphacinone is often applied in factories or agricultural and food production facilities where rats are present. When these products are used to address the rat problem, the compound can exist in the air, dust, or on material surfaces within the production area.
Additionally, during the storage and transportation of products containing Diphacinone, there may be leaks or dispersal of this chemical into the environment. This occurs when packaging, containers, or tools used to store and transport the product are not properly protected or sealed. Diphacinone can also be generated during the cleaning and maintenance of equipment in the factory, where rodenticides can adhere and be released into the air or onto work surfaces.

3. Industries that use Diphacinone in production
In production, Diphacinone is primarily used in industries that require pest control, especially for rodents. Some typical industries include agriculture, food and food processing, as well as the pharmaceutical industry. In agriculture, production facilities may use Diphacinone to control rats and other rodents, helping to protect crops and agricultural products from damage caused by animals.
The food processing industry is also one of the sectors where Diphacinone is present, as this is a place where rats, which pose a danger to product quality, are found. This chemical is used in food production plants to minimize the intrusion of rats into warehouses, storage areas, and production zones, aiming to ensure food safety and hygiene. In addition, some pharmaceutical industries also use Diphacinone in their pest control processes in drug production areas, where the production environment must be guaranteed to be free from the presence of harmful animals.
4. How does Diphacinone affect workers?
When workers come into contact with Diphacinone during their work, this chemical can cause serious health effects. Direct contact with Diphacinone can occur through inhalation, ingestion, or skin contact if proper protective measures are not taken. In the case of inhalation, dust or chemical vapors can enter the lungs, causing respiratory irritation, difficulty breathing, and symptoms such as coughing, runny nose, and sore throat.
When Diphacinone enters the body through the skin or mucous membranes, workers may experience symptoms such as itching, rashes, or dermatitis. Particularly, in cases of prolonged exposure or large doses, this compound can be toxic to the liver and kidneys. The chemical also affects the body’s circulatory system, as it interferes with the blood clotting process, posing a risk of hemorrhage, bruising, and even severe bleeding.
Furthermore, for workers with weakened immune systems or a history of medical conditions, exposure to Diphacinone increases the risk of cardiovascular diseases, blood clotting disorders, and internal organ damage. These effects not only diminish the health of workers but also affect their ability to work and their quality of life.
5. Permissible safe concentration of Diphacinone for human exposure
There is currently no specific and clear standard for the permissible safe concentration of Diphacinone for human exposure in all cases, due to the toxic nature of this chemical to the body. However, health and occupational safety agencies often recommend maximum acceptable exposure levels to minimize the risk of harm to workers’ health. Studies and guidelines from organizations such as OSHA (U.S. Occupational Safety and Health Administration) and the EPA (U.S. Environmental Protection Agency) focus on controlling the concentration of Diphacinone in the air and in the work environment, to ensure that workers are not exposed to excessively high concentrations that could lead to serious health problems.
Typically, occupational safety regulations will require production facilities using Diphacinone to comply with standards for the maximum permissible concentration in the air, to limit the dispersal of this chemical into the environment. These standards will vary depending on the country and the regulatory body, but the common goal is to ensure that the level of exposure to Diphacinone does not exceed a threshold that could be harmful to the health of workers over their working hours.

On a basic level, if working in an industrial environment, it is important to adhere to safety standards and limit exposure to Diphacinone. Organizations such as the Occupational Safety and Health Administration (OSHA) in the United States provide guidelines and safety principles to protect workers from the negative impacts of chemical substances.
6. Measures to minimize the health effects of Diphacinone on workers
To minimize the health effects of Diphacinone on workers, protective measures need to be implemented strictly in the work environment. First and foremost, providing adequate personal protective equipment such as gloves, masks, safety glasses, and protective clothing is crucial. This equipment helps prevent direct contact with the chemical, protecting workers from inhaling Diphacinone dust or vapor in the air.
In addition, improving the ventilation system in the work area also plays an important role in minimizing the level of Diphacinone dispersal into the air. It is necessary to maintain a well-ventilated workspace, using dust extraction and air filtration systems to remove pollutants, ensuring there is no accumulation of toxic chemicals in the work environment.
Training and raising awareness for workers about the risks and safety measures when working with Diphacinone is also an indispensable factor. Workers need to be instructed on how to recognize signs of poisoning and timely first aid measures in case of an incident. Production facilities also need to develop and implement safety procedures for using and storing Diphacinone, such as ensuring that products containing this chemical are stored correctly, avoiding leaks and unnecessary contact.
Finally, regular health check-ups for workers also help in the early detection of health effects due to exposure to Diphacinone. Blood tests and checks on liver, kidney, and circulatory system function will help monitor the health status of workers and allow for timely intervention if any problems arise.
Occupational safety training: Workers need to be trained and educated about the risks and safety measures when working with this type of chemical. This training should be provided periodically and regularly to ensure understanding and proper compliance with safety rules.
Periodically organize occupational environment monitoring in factories and enterprises, to collect and analyze factors harmful to workers, thereby adjusting to reduce the level of hazard to prevent occupational diseases for them.
7. Nationwide Occupational Environment Monitoring Center
Nam Viet’s Occupational Environment Monitoring Center is a professional unit for monitoring and measuring the quality of the working environment across all provinces in Vietnam. With a team of experienced monitoring specialists, the center uses modern measuring equipment, ensuring accuracy and reliability.
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In addition to providing monitoring services, the center also supports clients in planning, handling, and tracking occupational environment issues. With the motto “the customer is the center,” the center is concerned with customer satisfaction, meets all customer needs, and is committed to providing the best solutions for businesses.
With investment in technology, engineering, and human resources, Nam Viet’s monitoring center has become one of the reputable units in the field of occupational environment monitoring in Ho Chi Minh City with the following objectives:
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8. Quotation for occupational environment monitoring
To help businesses conduct occupational environment monitoring professionally and effectively, Nam Viet provides our valued customers with a price list for quality and reasonably priced occupational environment monitoring services.
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