Hexamethylene diamine (C6H16N2) is an important chemical in many industries, but it also poses risks to workers’ health. In this article, we will analyze in detail the impact of this chemical on health and the necessary preventive measures when working in a production environment. Let’s explore to protect health and improve occupational safety.
1. What is Hexamethylene diamine?
Hexamethylene diamine, with the chemical formula C6H16N2, is an organic compound belonging to the amine group. It is also known by another name, 1,6-hexamethylenediamine. This is an important compound in the chemical industry, often used as a raw material in the production process of polymers and plastics.
C6H16N2 has a molecular structure consisting of a long chain of six carbon (C) atoms and two amino (-NH2) groups located at both ends of the chain. This structure helps the compound easily react with other components to create products such as nylon 6,6, a common polymer in fabric and plastic production.
Hexamethylene diamine is in solid form, usually white crystals or powder, and is soluble in water. Its chemical properties allow it to participate in many chemical reactions, making it an important component in many industrial production processes.
However, despite its many industrial applications, long-term exposure to hexamethylenediamine can cause negative impacts on workers’ health. Therefore, understanding this chemical and implementing safety measures when working is extremely important.
| No. | Chemical name in Vietnamese | Chemical name in English | HS Code | CAS Number | Chemical Formula |
| 1. | Hexametylen diamin | Hexa methylene diamine | 29212200 | -648422 | C6H16N2 |
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2.What is the source of Hexamethylene diamine in the production process?
Hexamethylene diamine (C6H16N2) is usually produced in industrial plants through chemical synthesis processes from basic raw materials. The main source of this compound in the production process primarily comes from two main methods: synthesis from hexamethylene diisocyanate and the reaction between ethylene diamine and 1,6-hexanedione.
In the first method, hexamethylene diisocyanate (HDI) is the main input material. Through hydrolysis, HDI is converted into hexamethylene diamine. This method is often used in the production of polyurethane plastics and other polymer products, where hexamethylene diamine is an important component that helps improve the mechanical and chemical properties of the final product.
The second method involves the reaction between ethylene diamine and 1,6-hexanedione, creating hexamethylene diamine through a specific chemical synthesis process. This reaction takes place in a controlled environment, and the product obtained is pure hexamethylene diamine, ready to be put into industrial application.
During the production process, hexamethylene diamine can arise from various processing steps, such as when using these chemicals to prepare plastics or polymers. In particular, the handling and transportation of this compound can create dust or gas, increasing the risk of hexamethylene diamine spreading into the work environment. Therefore, protective and control measures need to be implemented to minimize exposure and protect worker health.

3. Industries that use Hexamethylene diamine in production
Hexamethylene diamine (C6H16N2) is an important chemical compound in many industries thanks to its special properties, especially its ability to react to create polymers and plastics. One of the main industries using hexamethylene diamine is the plastics and polymer production industry. This compound is used as a primary raw material to produce nylon 6,6, a common polymer with diverse applications such as apparel fabrics, cables, and high-tech plastic products.
The paint and coating manufacturing industry is also an important field that uses hexamethylene diamine. In paint and coating products, hexamethylene diamine acts as a curing agent or cross-linking agent, helping to improve the adhesion properties, durability, and abrasion resistance of the coating. This helps paint and coating products last longer and withstand harsh environmental conditions.
In addition, hexamethylene diamine is also used in the detergent and waterproofing agent manufacturing industry. In these products, this compound helps enhance the cleaning and waterproofing capabilities of the product, while contributing to improving the effectiveness of other chemicals present in the formula.
The pharmaceutical industry also involves hexamethylene diamine, especially in the synthesis of some organic compounds used in medicines and medical products. This compound is used in the production of drugs or chemicals with special properties that cannot be achieved by other methods.
However, the use of hexamethylene diamine in these industries also poses some occupational safety challenges, as this compound can cause negative health effects if not properly controlled. Therefore, businesses need to focus on applying safety measures and protecting the health of workers when working with hexamethylene diamine.
4. How does Hexamethylene diamine affect workers?
Hexamethylene diamine (C6H16N2) can cause significant health effects on workers if not managed and used properly. This compound, although important in many industrial applications, also contains potential health risks due to its chemical properties.
When exposed to hexamethylene diamine through inhalation, skin, or eyes, workers may experience irritation symptoms. Inhaling the dust or vapor of this compound can cause respiratory irritation, leading to symptoms such as coughing, difficulty breathing, or pneumonia. In cases of long-term exposure or high concentrations, chronic respiratory diseases can develop, seriously affecting the health of workers.
Direct skin contact with hexamethylene diamine can cause problems such as rashes, dermatitis, and allergic symptoms. This compound can strip moisture from the skin and cause severe irritation, especially if not protected by appropriate personal protective equipment. If hexamethylene diamine comes into contact with the eyes, it can cause a burning sensation, redness, and conjunctivitis.
Studies have shown that hexamethylene diamine can have toxic effects if ingested, leading to symptoms such as nausea, vomiting, and abdominal pain. Although ingestion is less likely in an industrial environment, it is still a factor to be considered.
To minimize negative health impacts, implementing safety measures is very important. This includes using personal protective equipment such as masks, gloves, and goggles, as well as ensuring good ventilation systems in work areas where hexamethylene diamine is used. Training and educating workers about the risks and preventive measures is also an essential part of protecting health in the work environment.
5. Permissible safe concentration of Hexamethylene diamine for human exposure
Managing the concentration of hexamethylene diamine (C6H16N2) in the work environment is very important to ensure the health and safety of workers. The permissible safe concentration is regulated by occupational safety and health organizations and agencies, and these standards help determine the maximum exposure level that does not cause serious health risks.
According to the standards of the Occupational Safety and Health Administration (OSHA) and other international organizations, the concentration of hexamethylene diamine in the air is specifically regulated. For example, OSHA has set the permissible exposure limit (PEL) for hexamethylene diamine at 10 mg/m³ averaged over an 8-hour workday, to protect workers’ health from the negative impacts of this compound. These limit values are established based on studies of the compound’s harm level to human health and the most effective protection capability in the work environment.
In addition to OSHA’s standards, other agencies such as the National Institute for Occupational Safety and Health (NIOSH) also provide exposure limit values. NIOSH recommends a maximum exposure limit for hexamethylene diamine of 5 mg/m³ over a 10-hour workday. The difference between the limit levels may depend on the type of work, working conditions, and other factors such as ventilation systems and personal protective measures.
To maintain the concentration of hexamethylene diamine within safe limits, factories and production facilities need to implement environmental control measures, including the use of effective ventilation systems, equipment maintenance, and regular checks of the compound’s concentration in the air. These measures help minimize exposure risk and protect the health of workers.
Besides, the use of personal protective equipment and the correct implementation of preventive measures also play an important role in maintaining a safe concentration level of hexamethylene diamine. Training and raising awareness for workers about the risks and protective measures are also essential factors to ensure health and safety in the work environment using this compound.

At a basic level, if working in an industrial environment, it is important to adhere to safety standards and limit exposure to Hexamethylene diamine. Organizations like the Occupational Safety and Health Administration (OSHA) in the United States provide safety guidelines and principles to protect workers from the negative impacts of chemical substances.
6. Measures to minimize the health effects of Hexamethylene diamine on workers
To minimize the negative health effects of hexamethylene diamine (C6H16N2) on workers, implementing protective and control measures is very important. These measures aim to ensure that workers are working in a safe environment, minimizing risks and protecting health effectively.
First of all, establishing and maintaining an effective ventilation system in work areas where hexamethylene diamine is used is essential. The ventilation system helps reduce the concentration of the compound in the air, ensuring that the hexamethylene diamine concentration does not exceed the permissible safe limit. In particular, ventilation systems must be regularly inspected and maintained to ensure effective operation.
Using personal protective equipment is an important measure to protect workers’ health. Equipment such as respirators, chemical-resistant gloves, and goggles must be fully provided and used correctly. Protective equipment helps prevent direct contact with hexamethylene diamine through the respiratory tract, skin, and eyes, thereby minimizing the risk of causing health problems.
Training and educating workers about the risks and preventive measures also play an important role in protecting health. Workers need to be instructed on ways to avoid exposure to hexamethylene diamine, how to use personal protective equipment correctly, and how to respond when an incident occurs. Organizing regular training sessions and updating information will help raise awareness and skills for workers.
In addition, risk control measures must be implemented during the production process. This includes controlling and monitoring the concentration of hexamethylene diamine in the air, while implementing preventive measures to prevent the leakage or dispersal of the compound in the work environment. Safe work procedures and the application of occupational health and safety regulations must also be strictly followed.
Occupational safety training: Workers need to be trained and educated on the risks and safety measures when working with this type of chemical. This training should be provided periodically and frequently to ensure understanding and compliance with safety rules.
Periodically organize occupational environment monitoring in factories and enterprises, collect and analyze factors harmful to workers, and from there, adjust to reduce hazard levels to prevent occupational diseases for them.
7. National Occupational Environment Monitoring Center
The Occupational Environment Monitoring Center of Nam Viet is a professional unit for monitoring and measuring the quality of the occupational environment across all provinces in Vietnam. With a team of experienced monitoring specialists, the center uses modern measuring equipment, ensuring accuracy and reliability.
REGISTER FOR OCCUPATIONAL ENVIRONMENT MONITORING SERVICE
In addition to providing monitoring services, the center also supports clients in planning, handling, and tracking occupational environment issues. With the motto “the customer is the center,” the center cares about customer satisfaction, meets all customer needs, and commits to providing the best solutions for businesses.
With investment in techniques, technology, and human resources, Nam Viet’s monitoring center has become one of the reputable units in the field of occupational environment monitoring in Ho Chi Minh City with the following objectives:
- We always value our brand reputation and the quality of our products and services.
- We provide our customers with the best and most suitable things possible.
- Along with a team of experienced Masters and Engineers with expertise, we desire to protect the environment and bring benefits to businesses.

- Coming to the Nam Viet Environmental Monitoring team, your company will receive professional service from experts in the monitoring field. At the same time, you will get the best cost incentives.
8. Quotation for occupational environment monitoring
To help businesses perform occupational environment monitoring professionally and effectively, Nam Viet provides customers with a quality and reasonably priced price list for occupational environment monitoring services.
- Our monitoring price list provides detailed information on the prices of the monitoring services we offer. This includes costs related to travel, measurement, analysis, and reporting of results. Customers can be completely assured of the accuracy and reliability of the monitoring result reports we provide.
- We are committed to always offering the most competitive and reasonable prices on the market, and we are always ready to advise and answer any questions about monitoring services quickly and professionally.
- With Nam Viet’s monitoring price list, customers can easily choose service packages that suit their needs. We commit to bringing customers the highest satisfaction with professional service quality.

