2-Methyl propane nitrile (C4H7N) is an important chemical in industrial production, but it poses many health risks to workers. This article will analyze the impact of this chemical on health, the risks of exposure, and how to protect oneself safely, helping workers to work effectively and sustainably.
1. What is 2-Methyl propane nitrile?
2-Methyl propane nitrile, with the chemical formula C₄H₇N, is an organic compound belonging to the nitrile group. It is a colorless or slightly pale yellow liquid with a characteristic odor and is highly volatile. This compound is commonly used in the chemical industry, especially in organic synthesis and the production of other intermediate compounds.
Structurally, 2-Methyl propane nitrile consists of a nitrile group (-CN) bonded to a branched carbon backbone. This gives it certain chemical reactivity and allows it to participate in many important synthesis reactions. Thanks to this property, it is widely used in the production of pharmaceuticals, pesticides, paints, plastics, and other industrial chemicals.
However, due to its special chemical properties, 2-Methyl propane nitrile can be hazardous to human health if not handled properly. Upon direct contact or inhalation of its vapors, workers may experience respiratory, skin, and nervous system problems.
| No. | Chemical Name in Vietnamese | Chemical Name in English | HS Code | CAS Number | Chemical Formula |
| 1. | Isobutyronitril (2-metyl propan nitril) | 2- Methyl propane nitrile | 29269000 | 78-82-0 | C4H7N |
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2. What are the sources of 2-Methyl propane nitrile in the production process?
In industrial production processes, the compound C₄H₇N can be generated from various sources, especially in chemical synthesis procedures. One of the main sources is the production of nitrile compounds, where the reaction between organic compounds containing appropriate functional groups and a cyanating agent can produce this product.
Additionally, this compound may appear as an intermediate in the synthesis of chemicals used in the production of pharmaceuticals, pesticides, and industrial plastics. Some solvent and adhesive manufacturing processes may also generate this compound as a byproduct or side product in chemical reactions.
Another source of generation is from chemical processing and purification activities in factories. During distillation, extraction, or raw material purification stages, this compound can evaporate into the air or exist in industrial waste if not strictly controlled.

3. Industries that use 2-Methyl propane nitrile in production
The compound C₄H₇N is used in many different industries, especially in the fields of chemical production and synthetic materials. In the pharmaceutical industry, it serves as an intermediate raw material in the synthesis of important organic compounds, contributing to the creation of many types of drugs and pharmaceutical substances.
In the chemical industry, this compound is used in the synthesis of other nitrile compounds, playing an important role in the production of solvents, catalysts, and specialty chemicals. It is also present in the paint and plastics industries, where it participates in the creation of polymer compounds and surface coatings, helping to improve the durability and resistance of materials.
Furthermore, the agricultural industry also uses this compound in the production of pesticides, especially insecticides and herbicides. These products require chemical compounds with high stability, and C₄H₇N is often used as a key component in the manufacturing process. In some other industries such as the production of adhesives, synthetic rubber, and fire-retardant materials, this compound also appears as an additive or intermediate in the manufacturing process.
4. How does 2-Methyl propane nitrile affect workers?
When exposed to the compound C₄H₇N in the workplace, workers can experience many negative health effects, depending on the level of exposure and the duration of work with this chemical. One of the most common effects is respiratory irritation upon inhaling vapors or dust containing this compound. Workers may experience symptoms such as coughing, difficulty breathing, sore throat, and lung discomfort. With long-term exposure without protective measures, the risk of lung damage and chronic respiratory problems can increase.
In addition to affecting the respiratory system, this chemical can also cause skin and eye irritation upon direct contact. Workers may experience redness, itching, rashes, or contact dermatitis. When it comes into contact with the eyes, this compound can cause severe irritation, leading to redness, tearing, or a burning sensation, and in severe cases can temporarily affect vision.
Regarding effects on the nervous system, prolonged exposure to high concentrations of this compound can lead to symptoms such as headache, dizziness, nausea, and fatigue. If exposure is severe, it can affect central nervous system function, impairing concentration and causing neurological disorders. Furthermore, when this chemical enters the body through inhalation or skin absorption, it can disrupt metabolism and affect the liver and kidneys, impairing the function of these organs over time.
5. Permissible safe concentration of 2-Methyl propane nitrile for human exposure
Currently, in the national technical regulations on permissible exposure limits for chemical factors in the workplace, there is no specific information on the permissible safe concentration of 2-Methyl propane nitrile (C₄H₇N). Therefore, to ensure worker safety, it is necessary to refer to international standards or apply general preventive measures when working with similar chemical compounds.

At a basic level, when working in an industrial environment, it is important to adhere to safety standards and limit exposure to Isobutyronitrile (2-methyl propanenitrile). Organizations such as the Occupational Safety and Health Administration (OSHA) in the United States provide guidelines and safety principles to protect workers from the negative effects of chemical substances.
6. Measures to minimize the health effects of 2-Methyl propane nitrile on workers
Minimizing the health effects of the compound C₄H₇N on workers requires a combination of engineering controls, work organization, and personal protective equipment. First and foremost, local exhaust and ventilation systems should be installed in the work area to limit the accumulation of chemical vapors in the air. Production processes should be designed to minimize the evaporation or leakage of chemicals, while applying closed-system measures to minimize release into the environment.
Workers must be fully equipped with personal protective equipment such as vapor-filtering masks, chemical-resistant gloves, safety goggles, and specialized protective clothing. Strict adherence to safety procedures when handling chemicals, including correct handling techniques, proper storage of the compound, and prompt handling of spills, helps minimize the risk of direct contact. Regular occupational safety training is also a crucial element, helping workers to be aware of potential hazards and know how to respond in case of an incident.
In addition, monitoring the work environment through periodic measurement of chemical concentrations is necessary to ensure that exposure levels remain within safe limits. Preventive medical measures such as regular health check-ups, especially assessing respiratory, neurological, and dermatological functions, help to detect negative effects early and take timely intervention measures. At the same time, the factory needs to have an emergency response plan for spills, ensuring that workers receive first aid promptly and are taken to a medical facility if necessary.
Occupational safety training: Workers must be trained and educated on the risks and safety measures when working with this type of chemical. This training should be provided periodically and regularly to ensure understanding and proper adherence to safety rules.
Periodically organize occupational environment monitoring in factories and enterprises, collect and analyze harmful factors for workers, and from there, adjust to reduce the level of harm to prevent occupational diseases for them.
7. National Occupational Environment Monitoring Center
The Occupational Environment Monitoring Center of Nam Viet is a professional unit specializing in monitoring and measuring the quality of the occupational environment across all provinces in Vietnam. With a team of experienced monitoring specialists, the center uses modern measuring equipment, ensuring accuracy and reliability.
REGISTER FOR OCCUPATIONAL ENVIRONMENT MONITORING SERVICES
In addition to providing monitoring services, the center also supports clients in planning, handling, and tracking occupational environment issues. With the motto “the customer is the center,” the center focuses on customer satisfaction, meets all customer needs, and is committed to providing the best solutions for businesses.
With investment in technology, engineering, and human resources, Nam Viet’s monitoring center has become one of the reputable units in the field of occupational environment monitoring in Ho Chi Minh City with the following objectives:
- We always value our brand reputation and the quality of our products and services.
- We provide our customers with the best and most suitable solutions possible.
- With a team of experienced Masters and Engineers with a desire to protect the environment and benefit businesses.

- With the Nam Viet Environmental Monitoring team, your company will receive professional service from experts in the monitoring field. At the same time, you will get the best cost incentives.
8. Quotation for Occupational Environment Monitoring
To help businesses conduct occupational environment monitoring professionally and effectively, Nam Viet offers our customers a price list for quality and reasonably priced occupational environment monitoring services.
- Our monitoring price list provides detailed information on the prices of the monitoring services we offer. This includes costs related to travel, measurement, analysis, and reporting of results. Customers can be completely assured of the accuracy and reliability of the monitoring result reports we provide.
- We are committed to always offering the most competitive and reasonable prices on the market, and we are also always ready to provide advice and answer any questions about our monitoring services quickly and professionally.
- With Nam Viet’s monitoring price list, customers can easily choose service packages that suit their needs. We are committed to bringing you the highest satisfaction with our professional service quality.

