2-methyl-1,3-butadiene (C5H8) is a common chemical in many industries, but few are aware of its potential danger to the health of workers. This article will shed light on the serious effects that this chemical can cause in the workplace.
1. What is 2-methyl-1,3-butadiene?
2-methyl-1,3-butadiene, with the chemical formula C5H8, is an organic compound belonging to the unsaturated hydrocarbon group. The molecular structure of 2-methyl-1,3-butadiene consists of 5 carbon atoms and 8 hydrogen atoms. It is a derivative of butadiene, in which a methyl group (-CH3) is attached to the number 2 position of the butadiene chain.
This compound is volatile and flammable, commonly used in the rubber and plastics manufacturing industries, as well as in the synthesis of other chemical compounds. The name “2-methyl-1,3-butadiene” comes from the arrangement of functional groups in the molecule, with “methyl” indicating the methyl group (-CH3) attached to the second carbon in the butadiene chain. This compound is also known as isoprene, an important raw material in the production of synthetic rubber.
Despite its many industrial applications, 2-methyl-1,3-butadiene poses potential risks to human health, especially for workers who are exposed to this chemical in their work environment.
| No. | Chemical Name in Vietnamese | Chemical Name in English | HS Code | CAS Number | Chemical Formula |
| 1. | Isopren | 2-methyl-1,3-butadiene | 29012400 | 78-79-5 | C5H8 |
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2-methyl-1,3-butadiene (C5H8) is a common chemical in many industries, but few are aware of its potential danger to the health of workers. This article will shed light on the serious effects that this chemical can cause in the workplace.
1. What is 2-methyl-1,3-butadiene?
2-methyl-1,3-butadiene, with the chemical formula C5H8, is an organic compound belonging to the unsaturated hydrocarbon group. The molecular structure of 2-methyl-1,3-butadiene consists of 5 carbon atoms and 8 hydrogen atoms. It is a derivative of butadiene, in which a methyl group (-CH3) is attached to the number 2 position of the butadiene chain.
This compound is volatile and flammable, commonly used in the rubber and plastics manufacturing industries, as well as in the synthesis of other chemical compounds. The name “2-methyl-1,3-butadiene” comes from the arrangement of functional groups in the molecule, with “methyl” indicating the methyl group (-CH3) attached to the second carbon in the butadiene chain. This compound is also known as isoprene, an important raw material in the production of synthetic rubber.
Despite its many industrial applications, 2-methyl-1,3-butadiene poses potential risks to human health, especially for workers who are exposed to this chemical in their work environment.
| No. | Chemical Name in Vietnamese | Chemical Name in English | HS Code | CAS Number | Chemical Formula |
| 1. | Isopren | 2-methyl-1,3-butadiene | 29012400 | 78-79-5 | C5H8 |
See more about our chemical safety training service according to Decree 113/2017/ND-CP
REGISTER FOR CHEMICAL OCCUPATIONAL SAFETY TRAINING ACCORDING TO DECREE 113
2. Where does 2-methyl-1,3-butadiene originate from during the production process?
In industrial production, 2-methyl-1,3-butadiene primarily arises from chemical processes such as petroleum cracking and the manufacturing of synthetic rubber. Specifically, in synthetic rubber production, isoprene is synthesized from petroleum or natural gas raw materials through reactions with special catalysts.
In addition, this compound can also be generated in plastics processing plants, where it is used as a primary raw material for producing synthetic plastic products. During this process, 2-methyl-1,3-butadiene may be released due to thermal decomposition or other chemical reactions related to the processing of unsaturated hydrocarbons.
Furthermore, 2-methyl-1,3-butadiene can also be present in industrial emissions from production processes, especially from plants that use high temperatures or cracking processes to treat raw materials. These emissions may contain volatile organic compounds, including 2-methyl-1,3-butadiene, which directly affect the environment and the health of workers if not properly controlled.

3. Industries that use 2-methyl-1,3-butadiene in production
2-methyl-1,3-butadiene is widely used in many industries, especially in the production of synthetic rubber. It is a key raw material in the synthesis of styrene-butadiene rubber (SBR) and polybutadiene, two common types of rubber used in the manufacturing of tires and other rubber products. The tire and automotive components industry is one of the sectors with the highest use of this chemical, as it helps improve the mechanical properties of the products.
In addition, 2-methyl-1,3-butadiene is also used in the production of synthetic plastics, particularly in the PVC industry. This compound participates in polymerization reactions, helping to create plastics with stable mechanical and thermal properties. The plastics and construction materials industries are also sectors that use 2-methyl-1,3-butadiene in their production processes.
Besides, some chemical industries also use 2-methyl-1,3-butadiene in the synthesis of other organic compounds, which are used to produce products such as paints, adhesives, solvents, and insulating materials.
4. How does 2-methyl-1,3-butadiene affect workers?
When exposed to 2-methyl-1,3-butadiene, workers can experience many adverse health effects. This chemical can enter the body through the respiratory tract by inhaling its vapors or through the skin upon direct contact during work. Initial symptoms of exposure to 2-methyl-1,3-butadiene include respiratory irritation such as coughing, shortness of breath, and chest pain. People working in environments with high concentrations of the chemical may face more serious respiratory problems like chronic bronchitis or asthma.
In addition, 2-methyl-1,3-butadiene can also have a negative impact on the nervous system. Long-term exposure to this chemical can lead to problems such as dizziness, headaches, and loss of concentration. Some studies also suggest that continuous, long-term exposure to 2-methyl-1,3-butadiene may increase the risk of cardiovascular diseases and cause long-term damage to heart function.
Furthermore, studies indicate that 2-methyl-1,3-butadiene may be a carcinogen, especially when workers are exposed to large amounts of this chemical over a long period. Those working in industries such as rubber, plastics, or other chemical manufacturing may be severely affected if they do not have appropriate protective measures in place.
5. Permissible safe concentration of 2-methyl-1,3-butadiene for human exposure
The permissible safe concentration of 2-methyl-1,3-butadiene for human exposure depends on the regulations and guidelines of international health and occupational safety organizations. According to the World Health Organization (WHO) and occupational health protection agencies, the permissible safe level of 2-methyl-1,3-butadiene in the workplace air is usually measured in parts per million (ppm) or parts per billion (ppb).
Specifically, the permissible exposure limit for 2-methyl-1,3-butadiene in the work environment typically ranges from 1 to 5 ppm over an 8-hour workday. This level is considered safe and does not cause serious health effects for workers with short-term exposure. However, if the concentration exceeds this level, the risk of causing health problems, especially respiratory and neurological diseases, increases significantly.

On a basic level, if working in an industrial environment, it is important to comply with safety standards and limit exposure to Isoprene. Organizations like the Occupational Safety and Health Administration (OSHA) in the United States provide guidelines and safety principles to protect workers from the negative effects of chemical substances.
6. Measures to minimize the health effects of 2-methyl-1,3-butadiene on workers
To minimize the health effects of 2-methyl-1,3-butadiene on workers, it is very important to apply protective measures and control the work environment. One of the most basic measures is to ensure adequate ventilation in the work area. Installing a ventilation system or using fume extractors can help reduce the concentration of the chemical in the air, minimizing the likelihood of workers inhaling the vapors of 2-methyl-1,3-butadiene.
In addition, factories need to control the concentration of chemicals in the air, ensuring that the level of 2-methyl-1,3-butadiene does not exceed the permissible safety limit. This can be achieved through continuous monitoring and implementing corrective measures when concentrations are found to exceed the permissible level. Regular inspection and maintenance of production equipment also help to minimize the release of the chemical into the environment.
Furthermore, the use of personal protective equipment for workers is extremely necessary. Equipment such as respirators, gloves, and protective clothing can help prevent direct contact with the chemical. This is especially important when workers have to work in areas with high concentrations of 2-methyl-1,3-butadiene.
Finally, training and raising awareness for workers about the health risks associated with 2-methyl-1,3-butadiene is a crucial element in prevention. Workers need to be instructed on preventive measures, the signs of chemical exposure, and the proper use of protective equipment to protect their own health.
Occupational safety training: Workers need to be trained and educated about the risks and safety measures when working with this type of chemical. This training should be provided periodically and regularly to ensure understanding and proper compliance with safety rules.
Periodically organize occupational environment monitoring in factories and enterprises, collecting and analyzing factors harmful to workers, thereby adjusting to reduce hazard levels to prevent occupational diseases for them.
7. National Occupational Environment Monitoring Center
Nam Viet’s Occupational Environment Monitoring Center is a professional unit for monitoring and measuring the quality of the working environment across all provinces in Vietnam. With a team of experienced monitoring specialists, the center uses modern measuring equipment, ensuring accuracy and reliability.
REGISTER FOR OCCUPATIONAL ENVIRONMENT MONITORING SERVICES
In addition to providing monitoring services, the center also supports clients in planning, handling, and tracking issues related to the occupational environment. With the motto “the customer is the center,” the center focuses on customer satisfaction, meeting all of the client’s needs, and committing to providing the best solutions for businesses.
With investment in techniques, technology, and human resources, Nam Viet’s monitoring center has become one of the reputable units in the field of occupational environment monitoring in Ho Chi Minh City with the following objectives:
- We always value our brand reputation and the quality of our products and services.
- We provide our customers with the best and most suitable solutions possible.
- With a team of experienced Masters and Engineers with a desire to protect the environment and benefit businesses.

- With the Nam Viet Environmental Monitoring team, your company will receive professional service from experts in the monitoring field. At the same time, you will get the best cost incentives.
8. Quotation for occupational environment monitoring
To help businesses carry out occupational environment monitoring professionally and effectively, Nam Viet offers our valued customers a price list for occupational environment monitoring services that is high-quality and reasonably priced.
- Our price list provides detailed information about the prices of the monitoring services we offer. This includes costs related to travel, measurement, analysis, and reporting of results. Customers can be completely assured of the accuracy and reliability of the monitoring result reports we provide.
- We are committed to always offering the most competitive and reasonable prices on the market, and we are also always ready to provide consultation and answer any questions about our monitoring services quickly and professionally.
- With Nam Viet’s price list, customers can easily choose service packages that suit their needs. We are committed to bringing our customers the highest satisfaction with professional quality service.

