Methyl acetate (C3H6O2) is a common chemical in many manufacturing plants. Do you know how it affects worker health? Discover the health risks, signs, and important preventive measures in this article to protect yourself and your colleagues.
1. What is Methyl acetate?
Methyl acetate, with the chemical formula C3H6O2, is an organic ester with a mild odor and is volatile. This chemical is known for its good solubility in many solvents, and it is often used in industry as a solvent in paints, varnishes, and in the production of other chemical products.
The chemical structure of methyl acetate includes a methyl group (CH3) linked to an acetate group (COO). This creates a compound with high solubility properties and it evaporates easily at room temperature. Methyl acetate is an effective solvent for dissolving many types of organic compounds, so it plays an important role in many industrial production processes.
Methyl acetate has characteristic physicochemical properties such as a low boiling point and good solubility in water and other organic solvents. Thanks to these features, methyl acetate is widely used in various industries, from paint manufacturing to the production of detergents and other chemical products. However, exposure to methyl acetate also needs to be strictly controlled due to the potential health risks it can pose to workers.
| No. | Chemical Name (Vietnamese) | Chemical Name (English) | HS Code | CAS Number | Chemical Formula |
| 1. | Metyl axetat | Methyl acetate | 29150990 | 79-20-9 | C3H6O2 |
See more services chemical safety training according to Decree 113/2017/ND-CP
REGISTER FOR CHEMICAL OCCUPATIONAL SAFETY TRAINING ACCORDING TO DECREE 113
2. Where does Methyl acetate originate from in the production process?
Methyl acetate is often generated in industrial production processes, especially in the paint and varnish industry, where it serves as an important solvent. During the production of these products, methyl acetate is used to dissolve other components and create paint or varnish formulations with high stability and performance.
The main source of methyl acetate generation comes from chemical reactions in the factory. One of the main reactions is the esterification between methanol and acetic acid. In this process, methanol (CH3OH) reacts with acetic acid (CH3COOH) to produce methyl acetate (CH3COOCH3) and water. This is the basic reaction in the production of methyl acetate, and it is often carried out in specialized reaction equipment at chemical production facilities.
In addition, methyl acetate can also arise from activities using or handling chemicals during the production process. For example, when products containing methyl acetate are used, a small amount may evaporate into the air. This often occurs in storage areas, mixing areas, or in production processes that use methyl acetate.

3. Industries that use Methyl acetate in production
Methyl acetate is a chemical widely used in many industries thanks to its good solubility and rapid evaporation properties. One of the main industries that uses methyl acetate is the paint and varnish industry. In paint production processes, methyl acetate plays an important role as a solvent that helps dissolve solid components and adjust the viscosity of the final product. This not only helps improve paint quality but also enhances surface coating ability and adhesion.
The printing industry is also a significant user of methyl acetate. In the printing process, methyl acetate is used as a solvent for printing inks, helping the ink dry quickly and adhere easily to various surfaces. The presence of methyl acetate in printing inks helps create prints with vibrant colors and high durability, meeting the demands of commercial and industrial printing applications.
In addition, methyl acetate is also used in the detergent and cleaning products industry. In cleaning products, methyl acetate acts as a solvent to help clean stains and grease, while improving the effectiveness of active ingredients. This chemical is also used in the plastics and rubber manufacturing industry, where it plays a role in the fabrication and processing of special types of plastics and rubber.
4. How does Methyl acetate affect workers?
Methyl acetate, although an effective solvent in many industries, can also cause negative impacts on workers’ health if not managed and used properly. Exposure to methyl acetate can lead to serious health problems, especially when exposure levels are high or prolonged.
One of the main effects of methyl acetate is respiratory irritation. When inhaling methyl acetate vapor, workers may experience symptoms such as coughing, difficulty breathing, and sore throat. In severe cases, long-term exposure can lead to chronic bronchitis or more serious respiratory problems.
For the skin and eyes, methyl acetate can cause irritation and redness, eye inflammation, and a burning sensation. If in direct contact with the skin, this chemical can cause the skin to become dry and cracked, creating conditions for infections or allergic reactions. For the eyes, methyl acetate can cause pain, redness, and itching, and even lead to corneal damage if not treated promptly.
Besides the direct impacts, methyl acetate can also cause problems related to the central nervous system. Prolonged exposure to high levels of methyl acetate can lead to symptoms such as headache, dizziness, and nausea. These symptoms can affect the ability to work and the performance of workers, while also increasing the risk of occupational accidents.
To minimize the risks associated with methyl acetate, preventive measures such as using good ventilation systems, wearing personal protective equipment, and maintaining safe work procedures are essential. In addition, providing adequate training and information to workers about the risks and how to protect themselves is very important to ensure health and safety in the working environment.
5. Permissible safe concentration of Methyl acetate for human exposure
Determining the permissible safe concentration of methyl acetate for exposure is very important to protect worker health and ensure a safe working environment. Regulatory agencies and health organizations have set standards and limits on the concentration of methyl acetate in the air to minimize health risks.
According to the standards of the World Health Organization (WHO) and occupational health protection agencies such as OSHA (Occupational Safety and Health Administration) and ACGIH (American Conference of Governmental and Industrial Hygienists), the concentration of methyl acetate in the air needs to be strictly controlled. The permissible concentration limit for methyl acetate is usually determined by two main indices: the Time-Weighted Average (TWA) and the Short-Term Exposure Limit (STEL).
Specifically, according to OSHA, the maximum permissible concentration of methyl acetate in the work environment is 200 parts per million (ppm) as a time-weighted average over an 8-hour work period. This is the concentration level to which workers can be exposed for long periods without experiencing negative health effects. For the short-term maximum concentration, OSHA sets the maximum level at 400 ppm for a 15-minute period. This helps ensure that even with short-term exposures to higher concentrations, workers do not face serious health risks.
In addition to OSHA’s standards, ACGIH recommends a maximum permissible concentration of methyl acetate of 200 ppm for TWA and 400 ppm for STEL, similar to OSHA’s regulation. These limits are based on studies of the health effects of methyl acetate and are established to protect workers from the potential risks of exposure to this chemical.
To ensure a safe working environment, companies and factories need to regularly check the concentration of methyl acetate in the air, use accurate measurement equipment, and implement control measures to keep the chemical concentration within safe limits. In addition, providing training to workers on preventive measures and how to use personal protective equipment is also an important factor in maintaining occupational safety and protecting health.
At a basic level, if working in an industrial environment, it is important to comply with safety standards and limit exposure to Methyl acetate. Organizations like the Occupational Safety and Health Administration (OSHA) in the United States provide guidelines and safety principles to protect workers from the negative impacts of chemical substances.
6. Measures to minimize the impact of Methyl acetate on workers’ health
To minimize the impact of methyl acetate on workers’ health, implementing preventive and control measures is extremely important. These measures not only help protect workers’ health but also ensure a safe and efficient working environment.
First, maintaining an effective ventilation system in the work area is one of the most important measures. A ventilation system helps dilute and remove methyl acetate vapors from the air, thereby reducing the concentration of this chemical to a safe level. The ventilation system needs to be designed and maintained periodically to ensure effective operation, especially in areas where methyl acetate is used or processed.
Second, the use of personal protective equipment (PPE) is necessary to reduce direct contact with methyl acetate. Workers should wear dust masks and protective gloves when working with this chemical. For areas with high concentrations of methyl acetate, using respirators with specialized filters can help protect the respiratory tract from chemical vapors.
Third, training and raising awareness for workers about the risks associated with methyl acetate is very important. Workers need to be informed about how to use the chemical safely, recognize the signs of overexposure, and measures to take when an incident occurs. Training should also include emergency response procedures and how to use personal protective equipment correctly.
Fourth, implementing safe work procedures and checking chemical concentrations in the air is necessary. Companies should periodically check methyl acetate concentrations to ensure they do not exceed safe limits. If high concentrations are detected, corrective measures must be taken immediately, such as improving ventilation or adjusting work processes.
Finally, storing and handling methyl acetate properly also helps minimize health risks. This chemical should be stored in sealed containers, in well-ventilated areas, and away from heat sources. At the same time, measures must be in place to manage and dispose of waste containing methyl acetate safely to avoid leaks and environmental contamination.
Occupational safety training: Workers need to be trained and educated about the risks and safety measures when working with this type of chemical. This training needs to be provided periodically and regularly to ensure understanding and compliance with safety rules.
Periodically organize workplace environment monitoring in factories and enterprises, collect and analyze factors harmful to workers, thereby adjusting to reduce the hazard level to prevent occupational diseases for them.
7. Nationwide workplace environment monitoring center
Nam Viet’s workplace environment monitoring center is a professional unit in monitoring and measuring the quality of the working environment across all provinces in Vietnam. With a team of experienced monitoring specialists, the center uses modern measuring equipment, ensuring accuracy and reliability.
REGISTER FOR WORKPLACE ENVIRONMENT MONITORING SERVICE
In addition to providing monitoring services, the center also supports customers in planning, handling, and monitoring workplace environment issues. With the motto “the customer is the center,” the center cares about customer satisfaction, meets all customer needs, and commits to providing the best solutions for businesses.
With investment in techniques, technology, and human resources, Nam Viet’s monitoring center has been and is becoming one of the reputable units in the field of workplace environment monitoring in Ho Chi Minh City with the following objectives:
- We always value our brand reputation and the quality of our products and services.
- We provide customers with the best and most suitable things possible.
- Along with a team of experienced Masters and Engineers with a desire to protect the environment and benefit businesses.

- Coming to Nam Viet’s Environmental Monitoring team, your company will receive professional service from experts in the monitoring field. At the same time, you will get the best offers on costs.
8. Quotation for workplace environment monitoring
To help businesses conduct workplace environment monitoring professionally and effectively, Nam Viet provides customers with a quality and reasonably priced price list for workplace environment monitoring services.
- Our monitoring quotation table provides detailed information about the prices of the monitoring services we offer. Including costs related to travel, measurement, analysis, and reporting results. Customers can be completely assured of the accuracy and reliability of the monitoring result reports we provide.
- We commit to always offering the most competitive and reasonable prices on the market, and we are also always ready to advise and answer any questions about monitoring services quickly and professionally.
- With Nam Viet’s monitoring quotation table, customers can easily choose service packages that suit their needs. We commit to bringing customers the highest satisfaction with professional service quality.

