Nicotine sulfate (l-l-Methyl-2-(3-pyridyl)-pynolidine sulfate) is a toxic chemical that can seriously affect the health of workers in a production environment. This article will clarify its dangerous effects and effective health protection measures.
1. What is Nicotine sulfate (l-l-Methyl-2- (3-pyridyl)- pynolidine sulfate)?
The chemical formula C20H30N4O4S indicates that this is an organic compound belonging to the alkaloid group. It is composed of elements such as carbon (C), hydrogen (H), nitrogen (N), oxygen (O), and sulfur (S), characterized by the combination of pyridyl and pynolidine groups. The nitrogen atoms in this chemical structure create a potent toxic property, making it a substance that seriously affects health upon long-term exposure.
This compound is commonly used in agriculture as a pesticide due to its ability to be toxic to insects. However, direct contact with it in an industrial or manufacturing environment can be hazardous to the health of workers. The chemical groups in the structure of nicotine sulfate form strong bonds with organs in the body, leading to harmful effects when appropriate preventive measures are not taken.
| No. | Chemical Name in Vietnamese | Chemical Name in English | HS Code | CAS Number | Chemical Formula |
| 1. | Nicotin sunfat | Nicotine sulfate (l-l-Methyl-2- (3-pyridyl)- pynolidine sulfate) | 29339990 | 65-30-5 | C20H30N4O4S |
See more chemical safety training services according to Decree 113/2017/ND-CP
REGISTER FOR CHEMICAL OCCUPATIONAL SAFETY TRAINING ACCORDING TO DECREE 113
2. Where does Nicotine sulfate (l-l-Methyl-2- (3-pyridyl)- pynolidine sulfate) originate from in the production process?
This chemical typically appears during agricultural production or in processing industries that use pesticides. In pesticide manufacturing plants, nicotine sulfate is synthesized from nicotine extracted from the tobacco plant, combined with sulfuric acid to form the sulfate salt. This process converts nicotine into a form that is easy to use and highly effective in killing insects.
Additionally, in production facilities that use nicotine sulfate, the main source of this substance can come from the handling and storage of nicotine-containing products, such as pesticides or products containing tobacco components. Leaks or non-compliance with occupational safety regulations can cause nicotine sulfate to be released into the air or onto equipment surfaces, creating an exposure risk for workers during the production process.

3. Industries that use Nicotine sulfate (l-l-Methyl-2- (3-pyridyl)- pynolidine sulfate) in production
This chemical is primarily used in the agricultural and pesticide manufacturing industries. In the agricultural sector, nicotine sulfate is used to formulate biological pesticides. It is particularly effective in killing insects such as aphids, thrips, and pests on crops, thanks to its potent toxic effect on their nervous systems. Therefore, pesticide manufacturing plants or agricultural processing facilities frequently use nicotine sulfate as a key ingredient in their products.
In addition, some food processing industries may also use nicotine sulfate in their processing or preservation procedures. However, the use of nicotine sulfate in these industries requires strict adherence to occupational safety and food hygiene regulations to avoid product contamination and the risk of harm to consumers.
In the tobacco manufacturing industry, nicotine sulfate may appear as an intermediate in the process of extracting nicotine from tobacco leaves. Although it is not a main component in the processing, it can still be generated during certain production stages if not strictly controlled.
4. How does Nicotine sulfate (l-l-Methyl-2- (3-pyridyl)- pynolidine sulfate) affect workers?
When exposed to this chemical, workers in the pesticide, agricultural, or food processing industries can face many serious health problems. One of the main effects is that nicotine sulfate can enter the body through the respiratory tract, skin, or mouth. When inhaled or in direct contact with the skin, this compound can cause mild to severe irritation. Initial symptoms often include coughing, difficulty breathing, dermatitis, and a feeling of nausea.
Furthermore, nicotine sulfate can also affect the nervous system of workers. This compound is a potent neurotoxin that can cause headaches, dizziness, disorientation, and sometimes fainting. Prolonged or repeated exposure can lead to more serious issues such as central nervous system disorders, reducing the cognitive and reflex abilities of workers.
A greater risk is when nicotine sulfate enters the body through the digestive system or skin, it can increase the risk of poisoning, affecting internal organs such as the liver, kidneys, and cardiovascular system. Symptoms of poisoning include nausea, vomiting, diarrhea, and in severe cases, can lead to damage to these organs, causing long-term health decline.
5. Permissible safe concentration of Nicotine sulfate (l-l-Methyl-2- (3-pyridyl)- pynolidine sulfate) for human exposure
The safe concentration of nicotine sulfate for human exposure depends on many factors, including exposure time, level of exposure, and protective measures in the work environment. Health and occupational safety agencies have issued permissible concentration limits to minimize health risks for workers. However, there is no absolute safe threshold, and the lower the exposure level, the better.
According to international standards such as those from OSHA (U.S. Occupational Safety and Health Administration) and NIOSH (National Institute for Occupational Safety and Health), the concentration of nicotine sulfate in the air should not exceed a certain threshold to avoid harmful health effects on workers. However, these regulations mainly apply to aerosol or dust forms of nicotine sulfate in the air, while skin or oral exposure also needs to be strictly controlled.

At a basic level, when working in an industrial environment, it is important to adhere to safety standards and limit exposure to Nicotine sulfate. Organizations such as the Occupational Safety and Health Administration (OSHA) in the United States provide guidelines and safety principles to protect workers from the negative impacts of chemical substances.
6. Measures to minimize the impact of Nicotine sulfate (l-l-Methyl-2- (3-pyridyl)- pynolidine sulfate) on workers’ health
To minimize the impact of nicotine sulfate on workers’ health, a series of protective and preventive measures must be implemented in the workplace. First, training and raising awareness among workers about the potential risks from this chemical is crucial. Employees need to clearly understand how nicotine sulfate affects health and the preventive measures to take upon exposure.
Another important measure is to control the work environment. Maintaining an effective ventilation system is necessary to reduce the concentration of nicotine sulfate in the air. Factories or production facilities using nicotine sulfate need to ensure they have adequate exhaust and dust filtration systems to remove this chemical from the workspace. This helps reduce the risk of inhalation or direct contact with nicotine sulfate.
In addition, the use of personal protective equipment (PPE) is extremely important. Workers should be equipped with chemical-resistant masks, gloves, safety glasses, and protective clothing to limit contact with nicotine sulfate. Furthermore, this personal protective equipment must be regularly maintained and inspected to ensure its effectiveness.
Implementing occupational hygiene measures is also an essential part. After each work shift, workers must change their protective clothing, shower, and wash their hands to remove any residual nicotine sulfate left on their bodies. Work areas also need to be cleaned regularly to prevent the accumulation of this chemical.
Finally, regular health monitoring of workers is very important. Production facilities should conduct periodic health check-ups to promptly detect signs of poisoning or health issues related to nicotine sulfate exposure. At the same time, health protection measures also need to be updated and adjusted according to the actual situation and new safety regulations.
Occupational safety training: Workers need to be trained and educated on the risks and safety measures when working with this type of chemical. This training should be provided periodically and regularly to ensure understanding and proper compliance with safety rules.
Periodically organize occupational environment monitoring in factories and enterprises, collect and analyze factors harmful to workers, and thereby adjust to reduce hazard levels to prevent occupational diseases for them.
7. National Occupational Environment Monitoring Center
Nam Viet’s Occupational Environment Monitoring Center is a professional unit specializing in monitoring and measuring the quality of the working environment across all provinces in Vietnam. With a team of experienced monitoring specialists, the center uses modern measuring equipment to ensure accuracy and reliability.
REGISTER FOR OCCUPATIONAL ENVIRONMENT MONITORING SERVICES
In addition to providing monitoring services, the center also assists clients in planning, handling, and tracking issues related to the occupational environment. With the motto “the customer is the center,” the center focuses on customer satisfaction, meets all customer needs, and is committed to providing the best solutions for businesses.
With investment in techniques, technology, and human resources, Nam Viet’s monitoring center has become one of the reputable units in the field of occupational environment monitoring in Ho Chi Minh City with the following objectives:
- We always value our brand reputation and the quality of our products and services.
- We provide our customers with the best and most suitable solutions possible.
- With a team of experienced and specialized Masters and Engineers, we aim to protect the environment and benefit businesses.

- By choosing the Nam Viet Environmental Monitoring team, your company will receive professional service from experts in the monitoring field. You will also receive the best cost incentives.
8. Quotation for Occupational Environment Monitoring
To help businesses conduct occupational environment monitoring professionally and effectively, Nam Viet provides our customers with a quality and reasonably priced quotation for occupational environment monitoring services.
- Our monitoring quotation provides detailed information on the pricing of the monitoring services we offer. This includes costs related to travel, measurement, analysis, and reporting of results. Customers can be completely assured of the accuracy and reliability of the monitoring result reports we provide.
- We are committed to always offering the most competitive and reasonable prices on the market, and we are also always ready to provide consultation and answer any questions about our monitoring services quickly and professionally.
- With Nam Viet’s monitoring quotation, customers can easily choose service packages that suit their needs. We are committed to bringing our customers the highest satisfaction with professional quality service.

