Working environment factors
How does O,O-Diethyl S-ethyl thiomethyl phosphorothioate affect workers’ health?
Apr
This article explores the impact of oo-Diethyl s-ethyl sulphonyl methyl phosphorothioate (C7H17O5PS2) on workers’ health in manufacturing facilities that use this chemical. It clarifies potential hazards and preventive measures to effectively protect workers’ health.
1. What is oo-Diethyl s-ethyl sulphonyl methyl phosphorothioate?
O,O-Diethyl S-ethyl sulphonyl methyl phosphorothioate, with the chemical formula C₇H₁₇O₅PS₂, is an organic compound belonging to the phosphorothioate group. Its molecular structure includes functional groups such as phosphorothioate, ethyl sulfonyl, and methyl. This compound is commonly known as phorate sulfone, an oxidized form of phorate, an organophosphate pesticide.
Phorate sulfone has the molecular formula C₇H₁₇O₄PS₃ and a molecular weight of approximately 292.38 g/mol. Its physical properties include very low water solubility (0.41 g/L at 25°C), density of 1.306 g/cm³, and refractive index of 1.5285 at 20°C. It has a boiling point of around 416.3°C at 760 mmHg, a flash point of 205.6°C, and an extremely low vapor pressure (9.32 × 10⁻⁷ mmHg at 25°C).
Chemically, phorate sulfone is a potent cholinesterase inhibitor, which can be toxic to the nervous system of both humans and animals if exposed directly or ingested. Therefore, its use and handling must strictly comply with chemical safety regulations and health protection measures.
| No. | Chemical Name (Vietnamese) | Chemical Name (English) | HS Code | CAS Number | Chemical Formula |
| 1. | oo-Dietyl s-etyl thiometyl photphorothioat | oo-Diethyl s-ethyl sulphonyl methyl phosphorothioate | 29309090 | 2588-06-09 | C7H17O5PS2 |
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2. Sources of oo-Diethyl s-ethyl sulphonyl methyl phosphorothioate in production processes
In the manufacturing process, the main source originates from chemical reactions between phosphorothioate-containing precursors and sulfonyl compounds. Typically, synthesis begins with the reaction of phosphorus trichloride (PCl₃) and sulfur (S) under inert atmosphere (e.g., nitrogen or argon) to produce thiophosphoryl chloride (PSCl₃). PSCl₃ is then distilled to remove impurities, yielding a colorless liquid. This reaction is clean, with high conversion efficiency and negligible by-products.
Next, PSCl₃ reacts with methanol (CH₃OH) in an alkaline environment to form a monoester, specifically O-methyl phosphorodichloridothioate, either continuously or in batches depending on production scale. Small amounts of diester may form due to slower monoester reactions.
Finally, the diester reacts with ammonia (NH₃) and sodium hydroxide (NaOH) to yield the final product with high purity and efficiency. Impurities such as triesters can be removed via distillation and washing steps.
In summary, the main sources of this compound during production arise from reactions between phosphorothioate precursors and sulfonyl compounds, particularly in the formation of PSCl₃, monoester, and diester.
3. Industries using oo-Diethyl s-ethyl sulphonyl methyl phosphorothioate
This compound is primarily used in agriculture, especially in the production of pesticides. It is utilized to create formulations that control harmful insects, protecting crops from pests.
Additionally, it is applied in scientific research, particularly in organic chemistry and biochemistry, for synthesizing structurally similar compounds or studying the mechanism of cholinesterase inhibitors.
4. Effects of oo-Diethyl s-ethyl sulphonyl methyl phosphorothioate on workers
This compound can seriously affect workers’ health upon direct or prolonged exposure.
As a cholinesterase inhibitor, it prevents the enzyme from breaking down acetylcholine, leading to accumulation in nerve junctions and causing neurological poisoning.
Acute symptoms include nausea, vomiting, fatigue, dizziness, headache, convulsions, respiratory difficulty, and potentially death if not treated promptly.
Chronic exposure may result in neurological disorders, memory impairment, psychological disturbances, and respiratory system issues.
5. Safe exposure limits for humans
Currently, there is no specific legal exposure limit for oo-Diethyl s-ethyl sulphonyl methyl phosphorothioate in Vietnam. Therefore, determining safe exposure levels should refer to international standards and industry best practices.
At a basic level, in industrial environments, adhering to safety standards and limiting exposure to oo-Diethyl s-ethyl sulphonyl methyl phosphorothioate is crucial. Organizations such as the **Occupational Safety and Health Administration (OSHA, USA)** provide guidelines and safety principles to protect workers from chemical hazards.
6. Measures to reduce the impact of oo-Diethyl s-ethyl sulphonyl methyl phosphorothioate on workers’ health
To minimize health risks, both personal protective equipment (PPE) and workplace controls are critical. Workers should wear gloves, masks, safety goggles, and protective clothing to limit direct contact. Compliance with safety procedures, proper use of PPE, and exposure control measures are essential.
Ensure adequate ventilation to reduce airborne concentrations, implement industrial hygiene practices such as handwashing and changing protective clothing after work. Training and raising awareness about risks and preventive measures is essential to maintain occupational safety.
Occupational safety training: Workers should receive regular and periodic training on risks and safety measures for handling this chemical.
Periodic workplace environmental monitoring is necessary to assess harmful factors, adjust exposure levels, and prevent occupational diseases.
7. National Occupational Environment Monitoring Center
The Nam Viet Occupational Environment Monitoring Center is a professional unit monitoring and measuring workplace environment quality across Vietnam. With experienced monitoring specialists and modern measurement equipment, the center ensures accuracy and reliability.
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Beyond monitoring, the center assists clients with planning, managing, and following up on workplace environment issues. Operating under the principle “customer-centric,” it ensures client satisfaction and optimal solutions.
With technical investment and skilled personnel, Nam Viet has become a reputable unit for occupational environment monitoring in Ho Chi Minh City, focusing on:
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8. Pricing for occupational environment monitoring
To help businesses conduct professional and effective workplace monitoring, Nam Viet provides detailed service pricing that is high-quality and reasonably priced.
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