Triethylenemelamine (C9H12N6) is a chemical used in many industries, but does it affect the health of workers? This article will analyze the impact of this substance in the work environment, the potential risks, and protective measures to ensure the safety of workers.
1. What is Triethylenemelamine?
Triethylenemelamine (C₉H₁₂N₆) is an organic compound of the triazine group, with a molecular structure consisting of a melamine ring bonded to three ethylenimine groups. It is a synthesized chemical used primarily in scientific research, medicine, and some industries.
This compound exists as a white crystalline solid or powder, is sparingly soluble in water but readily soluble in organic solvents such as ethanol, chloroform, and acetone. Thanks to its structure containing highly active aziridine groups, Triethylenemelamine can participate in many chemical reactions, especially in the pharmaceutical field and research on alkylating agents.
Triethylenemelamine was once used in cancer treatment due to its ability to affect the DNA of cells, causing genetic mutations and hindering the growth of cancer cells. However, due to its strong mutagenic properties, this substance can also be dangerous to human health upon exposure without appropriate protective measures. In an industrial environment, the use and control of Triethylenemelamine must strictly adhere to safety standards to minimize the risk of exposure.
| No. | Chemical Name in Vietnamese | Chemical Name in English | HS Code | CAS Number | Chemical Formula |
| 1. | Trietylenmelamin | Triethylenemelamine | 29336900 | 51-18-3 | C9H12N6 |
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2. Where does Triethylenemelamine originate from in the production process?
In industrial production, this compound is mainly synthesized from chemical precursors containing triazine and ethylenimine groups. The synthesis process usually takes place in a controlled environment with the participation of chemical catalysts to produce a high-purity final product.
The source of this compound can come from production stages in the pharmaceutical, chemical, and biological research industries. In the pharmaceutical industry, it can appear as an intermediate in the synthesis process of cancer treatment drugs or other alkylating compounds. When performing chemical reactions to create this compound, some by-products may be released into the work environment, increasing the risk of exposure for workers.
In addition, the handling, storage, and transportation of this compound can also be a source of emission in the production environment. When exposed to air or high temperatures, the compound can evaporate or decompose into other compounds, leading to its dispersion in the air. This is particularly concerning in manufacturing plants or laboratories, where strict control of working conditions is necessary to limit unwanted emissions.
Furthermore, during the treatment of industrial waste, if there is no proper management process, a small amount of the compound may remain in wastewater or solid waste, increasing the risk of contaminating the production environment. Indirect exposure from this waste source can occur when workers handle waste without adequate protective measures.

3. Industries that use Triethylenemelamine in production
This compound is used in many industries, especially in the fields of pharmaceuticals, chemicals, and biological research. In the pharmaceutical industry, it is used as an alkylating agent in the preparation of certain types of cancer treatment drugs. Thanks to its ability to affect the DNA of cells, this compound helps to inhibit the growth and division of cancer cells, contributing to the research and development of effective treatment therapies.
In the chemical industry, this compound serves as an intermediate in the synthesis of organic compounds with high biological activity. It can be used in the production of pesticides, polymer stabilizers, and some other industrial chemical products. Due to its high reactivity, this compound is usually handled in a controlled production environment to ensure safety and maintain synthesis efficiency.
In addition, the fields of biological research and biotechnology also utilize this compound in experiments on genetics and molecular biology. Thanks to its ability to cause DNA mutations, it is used in studies to understand genetic mechanisms and develop new treatment methods. Cancer and molecular biology research laboratories often use this compound in tests to examine the effects of mutagenic agents on living cells.
Besides, some other industries such as the production of synthetic materials, adhesives, and coatings may also use this compound as an additive to improve the mechanical and chemical properties of the product. Depending on the technical requirements and production processes, the use of this compound in industries may vary, but all require strict control measures to ensure the safety of workers and the work environment.
4. How does Triethylenemelamine affect workers?
When exposed to this compound in the workplace, workers can be affected at various levels, depending on the concentration, duration of exposure, and the protective measures applied. The most common routes of exposure are through respiration, skin, and mucous membranes, especially in manufacturing plants or laboratories where this compound is used frequently.
Inhaling vapor or dust containing this compound can cause irritation to the respiratory system, leading to symptoms such as coughing, difficulty breathing, a sore throat, and in severe cases, can cause lung damage. If exposure is prolonged without adequate protective measures, workers are at risk of developing respiratory-related diseases, including chronic bronchitis or other respiratory complications.
Skin contact is also a significant risk, especially as this compound can cause irritation or allergic reactions, leading to dermatitis, redness, itching, or peeling. Cases of high-concentration or prolonged exposure can damage the skin’s natural protective layer, making workers more susceptible to infections or more serious dermatological diseases.
In addition to immediate effects, this compound can also have long-term health impacts if there is regular exposure without appropriate protective measures. One of the biggest risks is its effect on the genetic system, due to its ability to cause cell mutations. This can increase the risk of developing cancers or cellular disorders, especially for those exposed to this compound over a long period.
In some cases, workers may experience symptoms such as headaches, nausea, dizziness, or impaired neurological function if poisoned at a high level. These symptoms can affect work performance as well as the quality of life of workers, especially when they are not fully aware of the danger level of this compound in the work environment.
5. Permissible safe concentration of Triethylenemelamine for human exposure
Currently, there is no specific information on the permissible safe concentration for exposure to Triethylenemelamine (TEM) in the workplace. However, as TEM is known for its mutagenic and highly toxic properties, exposure to this compound must be strictly controlled. Occupational safety regulatory agencies typically establish exposure limits for chemical substances based on research into their toxicity and health effects. In the absence of a specific limit for TEM, general preventive measures for highly toxic substances should be applied, including the use of personal protective equipment, effective ventilation systems, and regular monitoring of the work environment to ensure that the concentration of the hazardous substance is kept as low as possible.

On a basic level, if working in an industrial environment, adhering to safety standards and limiting exposure to Triethylenemelamine is important. Organizations like the Occupational Safety and Health Administration (OSHA) in the United States provide guidelines and safety principles to protect workers from the negative impacts of chemical substances.
6. Measures to minimize the health effects of Triethylenemelamine on workers
To minimize the health effects of Triethylenemelamine on workers, it is necessary to implement several important measures in the workplace. First and foremost, ensuring an effective ventilation system is essential to reduce the concentration of the chemical in the air. Using local exhaust ventilation systems, especially in production areas where Triethylenemelamine is used, will help to dilute and remove chemical vapors, limiting worker exposure.
In addition, providing workers with adequate personal protective equipment is very important. Chemical vapor respirators, gloves, safety glasses, and protective clothing must be used to prevent direct contact with Triethylenemelamine. This equipment helps protect workers from harmful effects on the skin, eyes, and respiratory tract.
Furthermore, training and raising awareness among workers about the risks associated with Triethylenemelamine is also very important. Workers need to be trained to recognize the signs of poisoning or irritation from this chemical and know how to react correctly in case of exposure. Training programs should be organized regularly and include both theoretical knowledge and practical application, helping workers to identify and respond promptly to emergency situations.
Finally, monitoring and checking the concentration of Triethylenemelamine in the workplace air is necessary. Gas concentration measuring devices must be used regularly to ensure that the chemical level is always at a safe level. When a concentration exceeding the permissible level is detected, corrective measures such as improving ventilation and minimizing the source of Triethylenemelamine must be implemented immediately.
All these measures not only help protect the health of workers but also enhance work productivity and create a safe and effective working environment.
Occupational safety training: Workers need to be trained and educated on the risks and safety measures when working with this type of chemical. This training should be provided periodically and regularly to ensure understanding and proper compliance with safety rules.
Periodically organize occupational environment monitoring in factories and enterprises, collect and analyze factors harmful to workers, thereby adjusting to reduce the level of hazard to prevent occupational diseases for them.
7. National Occupational Environment Monitoring Center
Nam Viet’s Occupational Environment Monitoring Center is a professional unit for monitoring and measuring the quality of the working environment across all provinces in Vietnam. With a team of experienced monitoring specialists, the center uses modern measuring equipment, ensuring accuracy and reliability.
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In addition to providing monitoring services, the center also assists clients in planning, handling, and tracking occupational environment issues. With the motto “the customer is the center,” the center focuses on customer satisfaction, meets all customer needs, and is committed to providing the best solutions for businesses.
With investment in technology, engineering, and human resources, Nam Viet’s monitoring center has become one of the reputable units in the field of occupational environment monitoring in Ho Chi Minh City with the following objectives:
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8. Quotation for Occupational Environment Monitoring
To help businesses carry out occupational environment monitoring professionally and effectively, Nam Viet offers our customers a quality and reasonably priced quotation table for occupational environment monitoring services.
- Our quotation table provides detailed information about the prices of the monitoring services we offer. This includes costs related to travel, measurement, analysis, and reporting of results. Customers can be completely assured of the accuracy and reliability of the monitoring result reports we provide.
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