Working environment factors
How does Cycloheximide affect workers’ health?
Feb
Cycloheximide (C15H23NO4) is a chemical used in manufacturing plants, but how does it affect the health of workers? This article will provide a detailed look at the risks and harms of cycloheximide to worker health and the necessary preventive measures.
1. What is Cycloheximide?
Cycloheximide (C15H23NO4) is a chemical compound belonging to the antibiotic group. It was first discovered in 1947 and has the chemical formula C15H23NO4, indicating that each molecule of cycloheximide consists of 15 carbon (C) atoms, 23 hydrogen (H) atoms, 1 nitrogen (N) atom, and 4 oxygen (O) atoms. Cycloheximide has a rather complex molecular structure, including carbon rings linked together to form a characteristic structural block.
This chemical is primarily known for its ability to inhibit protein synthesis in cells, especially in animals and plants. Cycloheximide acts on the translation process of the ribosome, preventing the production of new proteins in the cell. Therefore, cycloheximide is often used in cell biology research to investigate gene expression and the function of proteins.
In industry, cycloheximide may be used in pharmaceutical and biological production processes. However, because it is a compound that can be toxic to human health if not used correctly, it requires strict control in the work environment, especially in manufacturing plants.
| No. | Chemical Name in Vietnamese | Chemical Name in English | HS Code | CAS Number | Chemical Formula |
| 1. | Xycloheximit | Cycloheximide | 29419000 | 66-81-9 | C15H23NO4 |
See more: chemical safety training service according to Decree 113/2017/ND-CP
REGISTER FOR CHEMICAL SAFETY TRAINING ACCORDING TO DECREE 113
2. Where does Cycloheximide originate from in the production process?
During production, cycloheximide is mainly produced by microorganisms, especially fungal strains. Cycloheximide is a product of a biological process that occurs in species of the fungus Streptomyces, a genus of fungi capable of synthesizing antibiotic compounds. When these fungi are cultured in a suitable environment, they produce cycloheximide as a byproduct of their metabolic process.
In addition, cycloheximide can also be synthesized in industrial processes, where it is extracted from cultured microbial sources. The industrial production of cycloheximide requires strict control over temperature, humidity, and cultivation time to achieve optimal efficiency in harvesting the product. Due to its toxic nature, cycloheximide must be handled and used carefully to avoid negative impacts on human health in the production environment.
3. Industries that use Cycloheximide in production
Cycloheximide is used mainly in the biological and pharmaceutical industries. In the field of biological research, it is often used in cell and molecular research experiments. Specifically, cycloheximide is used to inhibit protein synthesis in animal and plant cells, thereby helping researchers to understand the process of translation and the function of proteins in the body.
Besides that, cycloheximide is also used in the production of drugs and biological preparations. During the production of these preparations, cycloheximide may be used to control or inhibit the growth of unwanted cells, helping to ensure product quality. Plants that produce biological drugs, vaccines, or cell culture preparations often use cycloheximide in their testing or production processes.
In addition, cycloheximide is also used in agricultural industries, especially in researching methods to control fungal diseases and other microorganisms harmful to crops. However, the use of cycloheximide in these industries requires strict control to avoid negative effects on the health of workers and the surrounding environment.
4. How does Cycloheximide affect workers?
When workers are in an environment where cycloheximide is used, they may experience negative health effects from exposure to this chemical. Cycloheximide can enter the body through the respiratory tract, skin, or ingestion if safety measures are not followed. When inhaling cycloheximide vapor or dust, workers may experience respiratory irritation symptoms such as coughing, shortness of breath, or rhinitis.
In addition, with long-term exposure to cycloheximide, negative effects can also impact the nervous system, causing symptoms such as headache, dizziness, or nausea. Cycloheximide can also cause skin and eye irritation if protective equipment such as gloves, safety glasses, and masks are not used sufficiently during work.
In particular, continuous exposure to cycloheximide can increase the risk of poisoning and damage to internal organs such as the liver and kidneys. Studies also show that cycloheximide has cytotoxic potential, and when accumulated in the body, it can impair the function of organ systems. Therefore, workers must be equipped with knowledge on how to use and prevent exposure when working with this chemical, while also strictly adhering to protective measures to minimize health risks.
5. Permissible safe concentration of Cycloheximide for human exposure
The permissible safe concentration of cycloheximide for human exposure depends on many factors, including the mode of contact (inhalation, skin contact, or eye contact), duration of exposure, and the level of protection for the worker. Health and occupational safety organizations, such as OSHA (U.S. Occupational Safety and Health Administration), have issued permissible limit concentrations for cycloheximide in the work environment.
According to safety standards, the concentration of cycloheximide in the air should not exceed 0.05 mg/m³ over an 8-hour work shift, to ensure it does not harm the health of workers. This is the maximum concentration to which workers can be exposed without experiencing serious health problems.
On a basic level, when working in an industrial environment, it is important to comply with safety standards and limit exposure to Cycloheximide. Organizations such as the Occupational Safety and Health Administration (OSHA) in the United States provide guidelines and safety principles to protect workers from the negative effects of chemical substances.
6. Measures to minimize the effects of Cycloheximide on worker health
To minimize the effects of cycloheximide on worker health, preventive and safety measures are very important throughout the production process. One of the first measures is to ensure the work environment has adequate ventilation. This helps to reduce the concentration of cycloheximide in the air and limit the possibility of workers inhaling this chemical. The ventilation system must be periodically checked to ensure its effectiveness and to minimize the risk of respiratory poisoning.
Besides that, the use of personal protective equipment such as chemical-resistant respirators, safety glasses, and chemical-resistant gloves is an essential factor. This equipment helps prevent cycloheximide from coming into direct contact with the skin, eyes, and respiratory tract of workers. In addition, it is necessary to provide adequate protective clothing and train workers on how to use and maintain protective equipment correctly.
In particular, implementing hygiene and cleaning procedures in the work area is also very necessary to minimize contact with cycloheximide. Surfaces, equipment, and work tools should be cleaned and checked regularly to remove residual chemicals. Workers should be instructed on personal hygiene measures, including frequent hand washing and changing protective clothing when necessary.
Finally, workers need to be trained on the potential risks when working with cycloheximide and how to recognize early symptoms of poisoning to take timely intervention measures. Regular health monitoring and reporting health problems to medical authorities also help to detect and address issues caused by exposure to cycloheximide.
Occupational safety training: Workers need to be trained and educated about the risks and safety measures when working with this type of chemical. This training should be provided periodically and regularly to ensure understanding and proper adherence to safety rules.
Periodically organize workplace environmental monitoring in factories and enterprises, collecting and analyzing factors harmful to workers, and from there, adjusting to reduce the level of harm to prevent occupational diseases for them.
7. National Workplace Environmental Monitoring Center
Nam Viet’s Workplace Environmental Monitoring Center is a professional unit for monitoring and measuring the quality of the working environment across all provinces in Vietnam. With a team of experienced monitoring specialists, the center uses modern measuring equipment, ensuring accuracy and reliability.
REGISTER FOR WORKPLACE ENVIRONMENTAL MONITORING SERVICE
In addition to providing monitoring services, the center also supports customers in planning, handling, and tracking workplace environmental issues. With the motto “the customer is the center,” the center is concerned with customer satisfaction, meeting all customer needs, and is committed to providing the best solutions for businesses.
With investment in technology, engineering, and human resources, Nam Viet’s monitoring center has become one of the reputable units in the field of workplace environmental monitoring in Ho Chi Minh City with the following objectives:
- We always value our brand reputation and the quality of our products and services.
- We provide customers with the best and most suitable things possible.
- Along with a team of experienced Masters and Engineers with a desire to protect the environment and benefit businesses.
- Coming to the Nam Viet Environmental Monitoring team, your company will receive professional service with experts in the field of monitoring. At the same time, you will get the best cost incentives.
8. Quotation for Workplace Environmental Monitoring
To help businesses carry out workplace environmental monitoring in a professional and effective manner, Nam Viet provides our customers with a quality and reasonably priced quotation for workplace environmental monitoring services.
- Our quotation provides detailed information on the prices of the monitoring services we offer. This includes costs related to travel, measurement, analysis, and reporting of results. You can be completely confident in the accuracy and reliability of the monitoring result reports we provide.
- We are committed to always offering the most competitive and reasonable prices on the market, and we are also always ready to provide consultation and answer any questions about monitoring services in the quickest and most professional manner.
- With Nam Viet’s quotation, you can easily choose the service packages that suit your needs. We are committed to bringing you the highest satisfaction with our professional service quality.
