How does Sodium Picramate affect workers’ health?

How does Sodium Picramate affect workers' health?
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Sodium picramate (C6H4N3NaO5) is a common chemical in the manufacturing industry, but can it harm workers’ health with long-term exposure? Let’s explore the potential health effects of this chemical and how to protect yourself in a work environment containing sodium picramate.

1. What is Sodium Picramate?

Sodium picramate, with the chemical formula C6H4N3NaO5, is a chemical compound belonging to the group of salts of picramic acid. This compound is formed by replacing the hydroxyl group (-OH) in picramic acid with a sodium group (Na). The molecular structure of sodium picramate consists of a benzene ring (C6H4) attached to three nitro groups (NO2) and a picramate group (C6H4N3) combined with a sodium atom (Na) through an ionic bond.

Sodium picramate is often used in several industries, particularly in the production of pharmaceuticals, pesticides, and other chemical applications. Although it is a useful compound in some manufacturing processes, due to its specific chemical properties, sodium picramate can have negative health effects if not used and stored properly.

With the chemical formula C6H4N3NaO5, sodium picramate is a substance that is readily soluble in water and can exist as a yellow powder. This property makes it an important raw material in several fields, but it also poses potential risks when workers are exposed to it long-term or do not use safety protection measures.

No. Chemical Name in Vietnamese Chemical Name in English HS Code CAS Number Chemical Formula
1. Natri picramat Sodium picramate 29089900 831-52-7 C6H4N3NaO5

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2. Where does Sodium Picramate originate from in the production process?

During the production process, this compound can arise from various sources, mainly in industries that use chemical compounds containing nitro and picramate groups. Manufacturing processes such as pharmaceutical synthesis, pesticide production, and some applications in the chemical industry are places where sodium picramate can be generated.

When chemical raw materials like picramic acid or compounds containing nitro groups are processed in high-temperature and high-pressure environments, sodium picramate can be formed as a byproduct or the main product during synthesis. These chemical reactions usually take place in industrial environments with strict controls, but sometimes direct contact with these substances or the byproducts of the reaction creates a risk of exposure for workers.

In addition, in some chemical waste recycling or treatment processes, sodium picramate can also arise as an unwanted compound. In these cases, ineffective waste management and control can lead to the presence of this compound in the production environment, thereby posing an exposure risk to workers.


3. Industries that use Sodium Picramate in production

Sodium picramate is used in certain industries, especially those related to chemicals and pharmaceuticals. In the pesticide manufacturing industry, this compound can be used to synthesize products that have insecticidal effects or kill other pests. This synthesis process involves using sodium picramate as a component in the main active compounds to control pests and diseases.

The pharmaceutical industry is also a field where sodium picramate is present, particularly in the research and production of some types of drugs. This compound may be used in the synthesis of active ingredients in drugs that have specific effects on certain medical conditions. However, the use of sodium picramate in the pharmaceutical industry requires a strict control process to ensure consumer safety.

Besides, in the chemical and material processing industries, sodium picramate may also appear as a component in the production process of some types of plastics or resins, although this application is not as common as in the pharmaceutical or pesticide industries. In these industries, the use of sodium picramate is often related to special chemical reactions that require intermediates like sodium picramate to complete the synthesis process.


4. How does Sodium Picramate affect workers?

When exposed to sodium picramate in the workplace, workers may experience negative health effects due to the toxic nature of this compound. Long-term exposure to sodium picramate can cause problems related to the respiratory system, skin, and eyes. The chemicals in sodium picramate can irritate the mucous membranes of the nose, throat, and lungs, leading to symptoms such as coughing, shortness of breath, or even pneumonia with excessive exposure.

In addition, sodium picramate can cause skin irritation, especially upon direct contact with the powder or a solution containing this compound. Prolonged or improper contact can lead to dermatitis, redness, itching, or sores on the skin surface. Allergic reactions may also occur, depending on the individual worker’s constitution.

One of the serious effects of sodium picramate is the risk of neurotoxicity if workers are continuously exposed without protective measures. Signs of neurotoxicity may include headaches, dizziness, concentration disorders, and problems with the central nervous system.


5. Permissible safe concentration of Sodium Picramate for human exposure

The permissible safe concentration of sodium picramate for human exposure is a critical issue in protecting workers’ health in work environments where this chemical is used. However, currently, regulations on the permissible safe concentration of sodium picramate in the air and on material surfaces have not been clearly defined in many countries. This is mainly due to a lack of extensive research and sufficient data on the health effects of this compound on humans under long-term exposure conditions.

Nevertheless, international health and occupational safety organizations often recommend that workers should not have long-term exposure to toxic chemicals without appropriate protective measures.

At a basic level, when working in an industrial environment, it is important to adhere to safety standards and limit exposure to Sodium Picramate. Organizations like the Occupational Safety and Health Administration (OSHA) in the United States provide guidelines and safety principles to protect workers from the negative impacts of chemical substances.


6. Measures to minimize the health effects of Sodium Picramate on workers

To minimize the health effects of sodium picramate on workers, preventive and protective measures in the workplace are extremely important. One of the most basic and effective measures is the use of personal protective equipment. Workers need to be fully equipped with dust masks or vapor-filtering respirators to prevent inhalation of sodium picramate particles in the air. In addition, protective gloves and goggles should also be used to avoid direct contact with this chemical, especially during handling or contact with solutions containing sodium picramate.

Besides using protective gear, the work environment also needs to be improved to minimize exposure levels. Production areas using sodium picramate need to be well-ventilated to help dilute and remove toxic substances from the air. The use of dust extraction or toxic fume extraction systems is very important in workshops where this chemical may be generated, helping to limit the accumulation of sodium picramate in the air, thereby reducing the risk of exposure for workers.

In particular, training and raising awareness for workers about the health risks of working with sodium picramate is also an important measure. Workers need to be equipped with knowledge about the symptoms of poisoning and the necessary first-aid measures upon exposure to this compound. Regular health check-ups also play an important role in the early detection of signs of health effects, helping to intervene in a timely manner and minimize long-term impacts.

Finally, strict adherence to occupational safety regulations and standards related to the use of sodium picramate will help minimize risks for workers. The production and storage processes for this chemical must be strictly controlled, ensuring that waste or byproducts do not adversely affect workers’ health.

Occupational safety training: Workers need to be trained and educated on the risks and safety measures when working with this type of chemical. This training should be provided periodically and regularly to ensure understanding and proper compliance with safety rules.

Periodically conduct workplace environment monitoring in factories and enterprises, collecting and analyzing factors harmful to workers, thereby adjusting to reduce hazard levels to prevent occupational diseases for them.


7. National Workplace Environment Monitoring Center

Nam Viet’s Workplace Environment Monitoring Center is a professional unit specializing in monitoring and measuring the quality of the working environment across all provinces in Vietnam. With a team of experienced monitoring specialists, the center uses modern measuring equipment, ensuring accuracy and reliability.

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In addition to providing monitoring services, the center also assists clients in planning, handling, and tracking workplace environment issues. With the motto “the customer is the center,” the center focuses on customer satisfaction, meeting all customer needs, and is committed to providing the best solutions for businesses.

With investment in techniques, technology, and human resources, Nam Viet’s monitoring center has become one of the reputable units in the field of workplace environment monitoring in Ho Chi Minh City with the following objectives:

  • We always value our brand reputation and the quality of our products and services.
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  • With a team of experienced Masters and Engineers with a desire to protect the environment and benefit businesses.
Official letter from the Department of Health agreeing to the announcement of eligibility to conduct workplace environment monitoring activities
  • With Nam Viet’s Environmental Monitoring team, your company will receive professional service from experts in the monitoring field. At the same time, you will get the best cost incentives.

8. Quotation for workplace environment monitoring

To help businesses conduct workplace environment monitoring professionally and effectively, Nam Viet offers our valued customers a price list for quality and reasonably priced workplace environment monitoring services.

  • Our quotation provides detailed information on the prices of the monitoring services we offer. This includes costs related to travel, measurement, analysis, and reporting of results. Customers can be completely assured of the accuracy and reliability of the monitoring result reports we provide.
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  • With Nam Viet’s quotation, customers can easily choose service packages that suit their needs. We are committed to bringing our customers the highest satisfaction with professional quality service.

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