Cyclohexylamine (C6H13N) is a common chemical in manufacturing plants, but long-term exposure can cause serious health effects for workers. This article will explore the effects of cyclohexylamine on the body and the necessary protective measures in the work environment.
1. What is Cyclohexylamine (Cyclohexanamine)?
Cyclohexylamine (Cyclohexanamine), with the chemical formula C6H13N, is an organic compound belonging to the amine group, structured with a cyclohexane ring attached to an amine group (-NH2). The structure of cyclohexylamine consists of a six-carbon ring (C6), in which five carbon atoms form the ring chain and one carbon is attached to the amine group. The chemical formula C6H13N indicates that each molecule of cyclohexylamine consists of 6 carbon atoms, 13 hydrogen atoms, and 1 nitrogen atom.
Cyclohexylamine is a colorless liquid with a strong odor and is volatile. It has strong alkaline properties and readily reacts with acids to form cyclohexylamine salts. Cyclohexylamine is used in many industrial applications such as a catalyst, an additive in plastics production, and in the production of pesticides and cleaning agents.
With the chemical formula C6H13N, cyclohexylamine is a compound that easily participates in chemical reactions, especially with acids, to form amine salts. However, due to its alkaline and volatile nature, cyclohexylamine can be harmful to health if not used and stored properly, especially in an industrial environment.
| No. | Chemical Name in Vietnamese | Chemical Name in English | HS Code | CAS Number | Chemical Formula |
| 1. | Xyclohexan amin | Cyclohexylamine (Cyclohexanamine) | 29213000 | 108-91-8 | C6H13N |
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2. Where does Cyclohexylamine (Cyclohexanamine) originate from in the production process?
During production, this compound is usually created through the reaction between cyclohexene (a hydrocarbon compound) and ammonia under high temperature and pressure conditions. This process is called an amination reaction, in which cyclohexene reacts with ammonia to form cyclohexylamine.
In addition, cyclohexylamine can also be produced through other synthesis methods, such as the reduction of amines from other compounds containing a nitro group or other amino-containing compounds. This production process is usually carried out in chemical plants, where there are strict control devices and procedures to ensure safety throughout the production process.
Besides that, in some cases, cyclohexylamine may appear as a byproduct during the production of other chemicals, such as in the production of detergents, pesticides, or polymers, when chemical reactions are incomplete or when ammonia is present in the production environment.

3. Industries that use Cyclohexylamine (Cyclohexanamine) in production
This compound is widely used in many industries due to its special chemical properties. One of the most common industries that use cyclohexylamine in production is the chemical industry. In this industry, cyclohexylamine is often used as a catalyst in the synthesis of other organic compounds, such as detergents, resins, and plastics. It is also used to produce polymers like polyurethanes, where this compound helps improve the durability and stability of the final product.
In addition, cyclohexylamine also plays an important role in the pesticide manufacturing industry. It is an important raw material in the synthesis of some types of pesticides, especially products used to protect crops from various insects and fungal diseases. The strong alkaline property of the compound helps to improve the effectiveness of the pesticide in killing harmful organisms.
In the pharmaceutical industry, cyclohexylamine is also used as an intermediate to synthesize medicines, especially types of antibiotics, analgesics, and anti-inflammatory drugs. It is used to synthesize complex chemical compounds, serving in the production of drugs that have a powerful effect on the body.
Furthermore, this compound also appears in the production of rubber products, plastics, and other compounds, where it acts as a stabilizer or an additive to improve the mechanical properties of the material.
4. How does Cyclohexylamine (Cyclohexanamine) affect workers?
When exposed to this compound, workers can experience negative health effects if safety measures are not followed. This compound can cause severe irritation to the skin, eyes, and respiratory tract. Direct contact with the skin or eyes can lead to dermatitis, rash, or an itching and burning sensation, while its vapor can irritate the mucous membranes of the eyes, nose, and throat.
In addition, if workers inhale cyclohexylamine vapor for a long time or at high concentrations, it can cause poisoning symptoms such as dizziness, nausea, coughing, shortness of breath, and headaches. Many studies show that long-term exposure to cyclohexylamine can be harmful to the nervous system, causing problems such as fatigue, weakness, and affecting concentration.
Cyclohexylamine can also affect the digestive system of workers if it is ingested or if fine particles containing this chemical are inhaled. Symptoms may include nausea, vomiting, abdominal pain, and diarrhea. Moreover, long-term exposure to this chemical can cause problems with the liver and kidneys, as these are the organs responsible for detoxifying and excreting harmful substances from the body.
Besides that, cyclohexylamine has strong alkaline properties, so when it comes into contact with body parts like the eyes or skin, it can cause severe damage. If not treated promptly, contact injuries can leave scars and affect the long-term health of the worker.
5. Permissible safe concentration of Cyclohexylamine (Cyclohexanamine) for human exposure
The safe concentration of this compound for human exposure is regulated by health and occupational safety agencies, such as the World Health Organization (WHO) and the U.S. Occupational Safety and Health Administration (OSHA). According to these standards, the maximum concentration to which a worker can be exposed in the work environment without posing a health risk is 10 parts per million (ppm) for the concentration in the air.
This concentration is determined based on studies of the toxicity and long-term effects of cyclohexylamine on human health. Regulatory agencies issue this safe concentration level to protect workers from serious harm from long-term exposure to the chemical, especially for problems with the respiratory tract, skin, and eyes. While working with cyclohexylamine, maintaining the concentration level below the regulated limit is very important to avoid side effects, including symptoms of poisoning or severe irritation.
However, in cases where the concentration of cyclohexylamine in the air exceeds the permissible safe level, workers must use personal protective equipment such as respirators, gloves, and safety goggles to minimize risk. Along with that, ventilation measures and regular checks of the chemical concentration in the air are also necessary to ensure a safe work environment.

On a basic level, when working in an industrial environment, it is important to comply with safety standards and limit exposure to Cyclohexylamine. Organizations such as the Occupational Safety and Health Administration (OSHA) in the United States provide guidelines and safety principles to protect workers from the negative effects of chemical substances.
6. Measures to minimize the effects of Cyclohexylamine (Cyclohexanamine) on worker health
To minimize the effects of this compound on worker health, preventive and protective measures must be strictly implemented in the work environment. One of the important measures is to ensure adequate ventilation in production areas, especially where cyclohexylamine is used. A good ventilation system helps to reduce the concentration of the chemical in the air, thereby limiting the inhalation of harmful vapors.
In addition, workers should fully use personal protective equipment (PPE) such as respirators, gloves, safety goggles, and protective clothing. Respirators help prevent the inhalation of cyclohexylamine vapor or dust, while gloves protect the skin from direct contact with the chemical. Safety goggles and protective clothing help protect the eyes and body from chemical splashes or vapors during work.
Training and raising awareness for workers is also an important factor. Workers need to be instructed on the health risks associated with cyclohexylamine and how to use protective equipment correctly. Ensuring that all employees clearly understand the safety measures will help minimize the risk of exposure to this chemical.
In addition, monitoring and periodically checking the chemical concentration in the air is an important measure to ensure that the work environment always remains at a safe level. Chemical concentration meters should be used to detect any changes in the cyclohexylamine concentration early, helping workers to take protective measures in a timely manner.
Finally, establishing and maintaining reasonable occupational hygiene procedures in the factory also plays an important role. Surfaces that come into contact with cyclohexylamine need to be cleaned regularly to avoid chemical buildup, and workers should also be instructed on how to wash their hands and change protective clothing after each shift.
Occupational safety training: Workers need to be trained and educated about the risks and safety measures when working with this type of chemical. This training should be provided periodically and regularly to ensure understanding and proper adherence to safety rules.
Periodically organize workplace environmental monitoring in factories and enterprises, collecting and analyzing factors harmful to workers, and from there, adjusting to reduce the level of harm to prevent occupational diseases for them.
7. National Workplace Environmental Monitoring Center
Nam Viet’s Workplace Environmental Monitoring Center is a professional unit for monitoring and measuring the quality of the working environment across all provinces in Vietnam. With a team of experienced monitoring specialists, the center uses modern measuring equipment, ensuring accuracy and reliability.
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In addition to providing monitoring services, the center also supports customers in planning, handling, and tracking workplace environmental issues. With the motto “the customer is the center,” the center is concerned with customer satisfaction, meeting all customer needs, and is committed to providing the best solutions for businesses.
With investment in technology, engineering, and human resources, Nam Viet’s monitoring center has become one of the reputable units in the field of workplace environmental monitoring in Ho Chi Minh City with the following objectives:
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8. Quotation for Workplace Environmental Monitoring
To help businesses carry out workplace environmental monitoring in a professional and effective manner, Nam Viet provides our customers with a quality and reasonably priced quotation for workplace environmental monitoring services.
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