Ammonium hydrogen difluoride (NH4HF2) is an important industrial chemical, but if not used and handled properly, it can cause serious health effects for workers. This article will analyze the risks and protective measures when working in an environment with NH4HF2.
1. What is Ammonium hydrogen difluoride?
Ammonium hydrogen difluoride, also known as ammonium bifluoride, has the chemical formula NH₄HF₂. It is a colorless inorganic compound that exists as crystals and is formed from the ammonium cation (NH₄⁺) and the bifluoride anion (HF₂⁻). This formula reflects the combination of the ammonium ion and the hydrogen difluoride ion, creating a salt with special properties.
The crystal structure of ammonium bifluoride is cubic, where each ammonium ion is surrounded by four fluoride ions in a tetrahedral structure. The hydrogen bonds between these ions create a strong network, contributing to the stability of the compound.
Ammonium bifluoride is prepared through the reaction of ammonia and hydrofluoric acid. This process produces a colorless salt with the formula NH₄HF₂, which is highly corrosive and used in many industrial applications, including glass etching and metal surface treatment.
| No. | Chemical Name in Vietnamese | Chemical Name in English | HS Code | CAS Number | Chemical Formula |
| 1. | Amon hydro diflorua | Ammonium hydrogen difluoride | 28261900 | 1341-49-7 | NH4HF2 |
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2. Where does Ammonium hydrogen difluoride originate from in the production process?
During the production of industrial products, this compound can be generated in various steps, especially in industries that use fluorine or fluorine-containing compounds. One of the main sources of this compound is in the production processes of cleaning agents, metal processing, or glass etching, where compounds like hydrofluoric acid are used.
When hydrofluoric acid (HF) gas reacts with other substances such as ammonia (NH₃) or other ammonium salts, the chemical reaction will create ammonium bifluoride (NH₄HF₂) as a byproduct. In addition, during the production of plastics or fluorine-containing compounds, this compound can also be formed if the environment is not well controlled. Therefore, the main source of ammonium bifluoride in manufacturing plants is typically from reactions involving hydrofluoric acid and fluorine-containing substances.

3. Industries that use Ammonium hydrogen difluoride in production
This compound is used in certain industries due to its special chemical properties. One of the main industries that use this compound is the metal processing industry, especially in surface cleaning and metal etching processes. The strong corrosive properties of this compound help to remove oxide layers or impurities on the metal surface, making it easier for these materials to receive coatings or surface finishes.
In addition, this compound is also widely used in the glass manufacturing industry, especially in the process of etching or treating the glass surface. Due to its strong cleaning and corrosive features, this compound helps create sharp and intricate patterns and images on glass.
The detergent manufacturing industry is also an important field for the use of this compound. Known for its ability to clean and remove stubborn stains, this compound is often used in industrial cleaning products or for special cleaning purposes. Besides, in the plastic and rubber manufacturing industry, this compound is also used to improve the properties of the final products.
4. How does Ammonium hydrogen difluoride affect workers?
When exposed to this compound, workers may face many health risks due to its corrosive and toxic nature. These chemicals can cause severe irritation to the skin, eyes, and respiratory system. If in direct contact with the skin, this compound can cause burns or damage to skin cells, and can also lead to inflammation or necrosis in cases of long-term exposure.
Inhaling vapor or dust from this compound can cause damage to the respiratory tract, from a feeling of shortness of breath and coughing, to more severe symptoms such as chronic bronchitis or pneumonia. Studies show that inhaling fluorine-containing compounds can lead to toxic accumulation in the body, affecting internal organs and causing serious long-term health problems.
In addition, this compound can also cause poisoning if accidentally swallowed. Such cases can lead to abdominal pain, nausea, or more severe symptoms, affecting the stomach and digestive system. Therefore, workers in environments where this compound is used must take full protective measures to minimize risks.
5. Permissible safe concentration of Ammonium hydrogen difluoride for human exposure
The permissible safe concentration for exposure to this compound is regulated in occupational health and environmental protection standards. According to international guidelines, the maximum permissible concentration of this compound in the air is 0.5 mg/m³ in the work environment for long-term exposure or during extended work shifts. This is the concentration to which a worker can be exposed without facing serious health risks.
In addition, in special cases, authorities also require the use of stricter protective measures such as good ventilation systems, personal protective equipment, and air quality control procedures to ensure that the exposure concentration does not exceed this safe level. These measures help to minimize the risk of inhaling dust or vapor of the compound, while also protecting the health of workers throughout the work process.
However, these standards may vary depending on the country and type of production, so factories and production facilities need to comply with local occupational safety regulations to ensure a healthy and safe working environment for their employees.

At a basic level, when working in an industrial environment, it is important to adhere to safety standards and limit exposure to Ammonium hydrogen difluoride. Organizations such as the Occupational Safety and Health Administration (OSHA) in the United States provide guidelines and safety principles to protect workers from the negative impacts of chemical substances.
6. Measures to minimize the effects of Ammonium hydrogen difluoride on worker health
To minimize the health effects of this compound on workers, protective measures must be strictly implemented from the start of production. One of the most important measures is to use an effective ventilation system in work areas with a high risk of exposure to this compound. Ensuring that the air in the work area is always circulating will help reduce the concentration of toxic substances in the air, thereby minimizing the risk of inhaling dust or vapor of the compound.
In addition, workers must use personal protective equipment fully and correctly, such as chemical respirators, gloves, safety goggles, and full-body protective clothing. This equipment helps prevent direct contact with the skin and eyes, while also protecting the respiratory tract from harmful substances.
Occupational safety training for workers also plays a crucial role in minimizing risks. Workers need to be instructed on safe work procedures, how to use personal protective equipment, and how to handle emergency situations such as exposure to this compound.
Finally, regular inspection and monitoring of the work environment are also very important. Devices for measuring the concentration of toxic substances in the air should be used regularly to ensure that the concentration of this compound is always at a safe level. When a level exceeding the permissible limit is detected, timely intervention measures must be taken to protect the health of workers.
Occupational safety training: Workers need to be trained and educated about the risks and safety measures when working with this type of chemical. This training should be provided periodically and regularly to ensure understanding and proper compliance with safety rules.
Periodically organize workplace environment monitoring in factories and enterprises, collect and analyze factors harmful to workers, and then adjust to reduce the hazard level to prevent occupational diseases for them.
7. Nationwide Workplace Environment Monitoring Center
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8. Quotation for workplace environment monitoring
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