Acetaldehyde (C2H4O) is a toxic chemical, common in manufacturing plants. This article will explore the serious effects of acetaldehyde on the health of workers, from short-term to long-term symptoms, and the necessary protective measures to minimize risks.
1. What is Acetaldehyde?
Acetaldehyde, with the chemical formula C2H4O, is a volatile organic compound with a characteristic mild odor and is highly flammable. It is one of the most common aldehydes, widely used in the chemical, pharmaceutical, and food industries. Acetaldehyde is primarily produced through the oxidation of ethanol or from other raw materials such as ethylene.
In terms of chemical structure, acetaldehyde has an aldehyde functional group (-CHO) attached to a methyl group (-CH3) and a hydrogen atom (-H). This structure makes acetaldehyde highly reactive with many other compounds and allows it to participate in important chemical processes in industrial production. Although it is best known for its role as an intermediate in the production of acetic acid, acetaldehyde also exists in the natural environment, for example, during alcohol fermentation.
Acetaldehyde is a toxic substance to human health upon long-term exposure, especially in work environments with high concentrations. It can cause respiratory, skin, and eye problems, and even poses a cancer risk with prolonged exposure. Therefore, a clear understanding of the properties of acetaldehyde and measures to control its concentration in the work environment is very important to protect the health of workers.
| No. | Chemical Name in Vietnamese | Chemical Name in English | HS Code | CAS Number | Chemical Formula |
| 1. | Axetaldehyt | Acetaldehyde | 29121200 | 75-07-0 | C2H4O |
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2. Where does Acetaldehyde originate from in the production process?
During the production process, acetaldehyde primarily arises from chemical reactions in the chemical and food processing industries. One of the main sources of acetaldehyde is the oxidation of ethanol, especially in factories that produce alcohol or ethanol-containing products such as pharmaceuticals and cosmetics. When ethanol is oxidized, it converts to acetaldehyde before further converting to acetic acid.
In addition, acetaldehyde can also be created during the production of plastics, synthetic rubber, and in the textile industry. Chemical reactions involving ethylene, a primary raw material in the plastics industry, can also produce acetaldehyde as a byproduct. In some cases, acetaldehyde is also generated during the processing of sugar-containing foods, such as during fermentation or food preservation.
Furthermore, acetaldehyde also comes from other industrial activities such as the production of chemicals, paints, and pharmaceuticals. Incomplete combustion processes, such as in power generation plants or traffic activities, can also release small amounts of acetaldehyde into the air.

3. Industries that use Acetaldehyde in production
Acetaldehyde is widely used in many different manufacturing industries, primarily in the chemical industry. One of the first to mention is the production of acetic acid. Acetaldehyde is one of the key raw materials in the synthesis of acetic acid, which is widely used in the production of plastics, paints, and other organic compounds.
The textile industry also uses acetaldehyde in the production of various fabrics and synthetic materials. Acetaldehyde helps to improve the properties of fabrics and is also used in the dyeing and finishing process. In addition, acetaldehyde is an important component in the production of polyester plastic compounds, which are used in the packaging, household goods, and other consumer products industries.
In the food industry, acetaldehyde also plays an important role. It is used as a flavoring agent in food products, beverages, and especially in alcohol production, where acetaldehyde appears as an intermediate product during fermentation. Besides, acetaldehyde is also present in some other industries such as pharmaceuticals, cosmetics, and tobacco, where it is used to create compounds with special properties.
4. How does Acetaldehyde affect workers?
When workers are exposed to acetaldehyde in the workplace, they can experience many serious health problems. In the short term, those who come into direct contact with acetaldehyde may suffer from irritation of the eyes, nose, and throat. Common symptoms include red eyes, sore throat, coughing, shortness of breath, and a burning sensation. These are immediate reactions to exposure to acetaldehyde vapor in the air.
With long-term or high-concentration exposure, acetaldehyde can cause damage to the respiratory system, leading to reduced lung function, difficulty breathing, and an increased risk of diseases such as chronic bronchitis or asthma. Workers in manufacturing plants that use acetaldehyde are at high risk of liver poisoning, because acetaldehyde can be metabolized into toxic compounds in the body, affecting liver function.
In addition, the effects of acetaldehyde are not limited to the respiratory system and liver but can also affect the central nervous system. Symptoms such as headaches, dizziness, fatigue, and loss of concentration are common in workers who are employed long-term in environments with high concentrations of acetaldehyde. In some studies, acetaldehyde is also considered a substance that may cause cancer, especially with long-term exposure to high concentrations, increasing the risk for workers to develop cancers related to the respiratory and digestive systems, and other organs.
5. Permissible safe concentration of Acetaldehyde for human exposure
The permissible safe concentration of acetaldehyde for human exposure is regulated by occupational safety and health management organizations. Safety limits are usually established to minimize risks to human health. However, these limits may vary by country and industry.
In the United States, the Occupational Safety and Health Administration (OSHA) has established a safety limit for acetaldehyde in the air of 25 parts per million (ppm) over an 8-hour time-weighted average (TWA). In addition, OSHA also sets a TWA limit of 15 ppm for the work environment in the detergent manufacturing industry.
The American Conference of Governmental Industrial Hygienists (ACGIH) has established a TWA safety limit for acetaldehyde of 1 ppm.
The National Institute for Occupational Safety and Health (NIOSH) proposes a TWA safety limit of 1 ppm for acetaldehyde.
However, these limits may vary depending on the country and industry. Therefore, it is very important to consult the specific regulations of each country and organization to ensure the safety of workers.

At a basic level, when working in an industrial environment, it is important to adhere to safety standards and limit exposure to Acetaldehyde. Organizations such as the Occupational Safety and Health Administration (OSHA) in the United States provide guidelines and safety principles to protect workers from the negative impacts of chemical substances.
6. Measures to minimize the effects of Acetaldehyde on worker health
To minimize the health effects of acetaldehyde on workers, protective measures must be strictly applied in the work environment. First and foremost, controlling the concentration of acetaldehyde in the air is one of the most important measures. Factories and production facilities must install ventilation systems, toxic gas extraction systems, and air quality control to ensure that the acetaldehyde concentration does not exceed the permissible safety limit.
In addition, workers should be fully equipped with personal protective equipment such as chemical respirators, specialized masks capable of filtering toxic gases, safety goggles, and gloves to minimize direct contact with acetaldehyde. The use of this personal protective equipment is essential in work areas with high concentrations of acetaldehyde.
Furthermore, managers and business owners need to organize training courses and provide guidance for workers on the health risks associated with acetaldehyde and effective prevention methods. Raising awareness about the dangers of acetaldehyde will help workers be more proactive in implementing measures to protect themselves.
Another important factor is periodic health check-ups for workers. Those who work in an environment with exposure to acetaldehyde need to have regular health checks to detect early symptoms of poisoning and to intervene promptly. Liver and lung function tests and general health check-ups are necessary steps to protect the health of workers.
Finally, regulations on health and occupational safety must be strictly adhered to. Authorities and management organizations need to conduct regular inspections and monitoring to ensure that measures to protect the health of workers are implemented correctly and fully.
Occupational safety training: Workers need to be trained and educated about the risks and safety measures when working with this type of chemical. This training should be provided periodically and regularly to ensure understanding and proper compliance with safety rules.
Periodically organize workplace environment monitoring in factories and enterprises, collect and analyze factors harmful to workers, and then adjust to reduce the hazard level to prevent occupational diseases for them.
7. Nationwide Workplace Environment Monitoring Center
Nam Viet’s workplace environment monitoring center is a professional unit specializing in the supervision and measurement of workplace environmental quality across all provinces in Vietnam. With a team of experienced monitoring specialists, the center uses modern measuring equipment, ensuring accuracy and reliability.
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8. Quotation for workplace environment monitoring
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