N – acetylanthranilic acid (C9H9NO3) is a common chemical in the manufacturing industry. However, long-term exposure to this substance can seriously affect workers’ health. This article will explore the health impacts of N – acetylanthranilic acid, along with the necessary protective measures.
1. What is N – acetylanthranilic acid?
With the chemical formula C9H9NO3, N – acetylanthranilic acid is an organic compound belonging to the amine group. This substance is known primarily in the chemical industry, especially in the production of dyes and pharmaceuticals. N – acetylanthranilic acid is created through the acetylation of anthranilic acid, a naturally occurring amino acid, often extracted from medicinal plants or synthesized in a laboratory.
Structurally, N – acetylanthranilic acid has an acetyl group (-COCH3) attached to an amino group (-NH2), creating a molecule with special chemical properties. The presence of the acetyl group not only affects the physical properties of the compound but also facilitates chemical reactions, making N – acetylanthranilic acid an important intermediate in many production processes.
In industry, N – acetylanthranilic acid is often used as a coloring agent for products such as fabrics, plastics, and printing inks. In addition, this compound also has applications in the production of various drugs, especially those with anti-inflammatory and analgesic effects.
| No. | Chemical Name in Vietnamese | Chemical Name in English | HS Code | CAS Number | Chemical Formula |
| 1. | Axít N – axetyl anthranilic | N – acetylanthranilic acid | 29242300 | 89-52-1 | C9H9NO3 |
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2. What is the source of N – acetylanthranilic acid in the production process?
This compound originates mainly from chemical synthesis, starting from anthranilic acid, a natural compound present in many types of plants. In industry, the production of N – acetylanthranilic acid typically occurs through an acetylation reaction, where anthranilic acid is treated with acetic acid or acetic anhydride. This process creates N – acetylanthranilic acid and water, while also lowering the pH of the solution.
N – acetylanthranilic acid not only appears in chemical production processes but can also arise from the use of products containing it. For example, in the pharmaceutical industry, when producing drugs that contain N – acetylanthranilic acid as a main component, this chemical can be released into the environment. Additionally, in the dye manufacturing industry, the decomposition of color compounds can also produce N – acetylanthranilic acid, increasing its concentration in the work environment.
The presence of N – acetylanthranilic acid in production processes is not only a result of chemical reactions but can also be due to inadequate cleaning and maintenance activities in the factory. If equipment or surfaces that come into contact with this chemical are not cleaned properly, residues can remain and affect the health of workers.

3. Industries that use N – acetylanthranilic acid in production
N – acetylanthranilic acid is widely used in many different industries, mainly due to its special chemical properties. One of the main industries that use this chemical is the textile dyeing industry. In the fabric dyeing process, N – acetylanthranilic acid is often used as an intermediate to produce various types of dyes. These dyes have good adhesion and create durable colors, thereby meeting the high-quality demands of the fashion industry.
Besides the textile dyeing industry, N – acetylanthranilic acid is also used in the pharmaceutical industry. This compound is an important ingredient in some drugs, especially those with anti-inflammatory and analgesic effects. The use of N – acetylanthranilic acid in drug production requires strict control processes to ensure the quality and safety of the final product.
In addition, N – acetylanthranilic acid is also present in other synthetic chemical production processes. For instance, it can be used as a catalyst or a starting material to produce other organic compounds. The plastics manufacturing industry also utilizes N – acetylanthranilic acid to create plastic products with special properties, helping to improve durability and heat resistance.
4. How does N – acetylanthranilic acid affect workers?
Although widely used in many different industries, N – acetylanthranilic acid can also have serious effects on workers’ health if not controlled and handled properly. When exposed to this compound, workers may experience various health problems, including both acute and chronic symptoms. Acute symptoms often appear immediately after exposure and can include skin irritation, itching, redness, and blistering. If dust or vapor of N – acetylanthranilic acid is inhaled, workers may feel shortness of breath, coughing, or a sore throat, indicating the chemical’s impact on the respiratory system.
In addition to acute symptoms, long-term exposure to N – acetylanthranilic acid can lead to more serious health problems. Research shows that prolonged exposure to this compound may increase the risk of liver and kidney diseases, and even reproductive disorders. This is particularly concerning in industries where workers are frequently exposed to the chemical without appropriate protective measures.
Studies also indicate that N – acetylanthranilic acid can have a negative impact on the nervous system, leading to feelings of fatigue, difficulty concentrating, and even symptoms of depression. This not only affects personal health but can also impact work productivity and the overall work environment.
5. Permissible safe concentration of N – acetylanthranilic acid for human exposure
The safe concentration of N – acetylanthranilic acid for human exposure is a critical issue in protecting workers’ health. Chemical safety standards are typically set by professional organizations and governments to minimize the risk of adverse health effects from exposure to hazardous chemicals.
According to current guidelines, the maximum permissible concentration of N – acetylanthranilic acid in the air is 5 mg/m³, based on an 8-hour workday. This means that workers should not be exposed to concentrations of N – acetylanthranilic acid higher than this level throughout their work shift. Exceeding the permissible concentration can lead to acute or chronic poisoning symptoms, increasing the risk of occupational diseases.
Furthermore, the safe concentration also needs to be considered based on factors such as the duration and route of exposure (inhalation, skin contact, etc.). If workers are in an environment with concentrations higher than the permissible level, additional protective measures are necessary, such as using personal protective equipment, effective ventilation systems, and organizing regular health check-ups to monitor their health status.
Manufacturers also need to comply with chemical safety regulations, including providing clear information about the safe concentration of N – acetylanthranilic acid in safety data sheets (SDS). This not only helps protect workers’ health but also ensures compliance with legal regulations related to chemical safety.

At a basic level, if working in an industrial environment, it is important to adhere to safety standards and limit exposure to N-acetylanthranilic acid. Organizations such as the Occupational Safety and Health Administration (OSHA) in the United States provide guidelines and safety principles to protect workers from the negative effects of chemical substances.
6. Measures to mitigate the health effects of N – acetylanthranilic acid on workers
To mitigate the health effects of N – acetylanthranilic acid on workers, safety and preventive measures are essential. First and foremost, raising awareness about the potential risks of this chemical is crucial. Companies should organize regular training programs for their employees to help them understand the properties and harmful effects of N – acetylanthranilic acid, as well as the necessary personal protective measures when working in an environment where this chemical is used.
Another effective measure is the use of appropriate personal protective equipment (PPE). Workers should be equipped with masks, gloves, safety glasses, and chemical-resistant clothing to minimize contact with N – acetylanthranilic acid. Especially in cases where the chemical concentration in the air exceeds safe levels, the use of protective equipment will play a critical role in safeguarding health.
The ventilation system in the factory also needs to be properly designed and maintained to ensure fresh air and reduce the concentration of N – acetylanthranilic acid in the air. Installing exhaust fans, openable windows, and air filtration systems are effective solutions for improving air quality in the work environment.
In addition, controlling the production process is also very important. Companies need to implement measures to minimize the release of N – acetylanthranilic acid into the environment, such as using advanced production technology and optimizing chemical handling processes. Performing regular maintenance on machinery and equipment also helps prevent chemical leaks.
Finally, regular health monitoring for workers is necessary to detect any early signs of abnormalities and to take timely intervention measures. Regular health check-up programs not only help ensure the safety of workers but also create a safe and healthy working environment for them. By combining preventive measures, control, and health monitoring, the negative impact of N – acetylanthranilic acid on workers’ health can be effectively minimized.
Occupational safety and health training: Workers need to be trained and educated on the risks and safety measures when working with this type of chemical. This training should be provided periodically and regularly to ensure understanding and proper adherence to safety rules.
Periodically organize occupational environment monitoring in factories and enterprises, to collect and analyze factors harmful to workers, and from there, adjust to reduce the level of hazard to prevent occupational diseases for them.
7. National Occupational Environment Monitoring Center
The Occupational Environment Monitoring Center of Nam Viet is a professional unit for monitoring and measuring the quality of the working environment across all provinces in Vietnam. With a team of experienced monitoring specialists, the center uses modern measurement equipment, ensuring accuracy and reliability.
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In addition to providing monitoring services, the center also assists clients in planning, addressing, and tracking issues related to the occupational environment. With the motto “the customer is the center,” the center is concerned with customer satisfaction, meeting all customer needs, and is committed to providing the best solutions for businesses.
With investment in techniques, technology, and human resources, the Nam Viet monitoring center has been and is becoming one of the reputable units in the field of occupational environment monitoring in Ho Chi Minh City with the following objectives:
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- Along with a team of experienced and specialized Masters and Engineers who wish to protect the environment and benefit businesses.

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8. Quotation for Occupational Environment Monitoring
To help businesses carry out occupational environment monitoring professionally and effectively, Nam Viet provides our customers with a quotation for quality and reasonably priced occupational environment monitoring services.
- Our monitoring quotation provides detailed information on the prices of the monitoring services we offer. It includes costs related to travel, measurement, analysis, and reporting of results. Customers can be completely assured of the accuracy and reliability of the monitoring result reports we provide.
- We are committed to always offering competitive and reasonable prices on the market, and we are also always ready to provide consultation and answer any questions about our monitoring services quickly and professionally.
- With Nam Viet’s quotation, customers can easily choose service packages that suit their needs. We are committed to bringing our customers the highest satisfaction with our professional service quality.

